HCSGD entry for CTNNA1

1. General information

Official gene symbolCTNNA1
Entrez ID1495
Gene full namecatenin (cadherin-associated protein), alpha 1, 102kDa
Other gene symbolsCAP102
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001541Ovarian follicle developmentIEAbiological_process
GO:0001669Acrosomal vesicleIEAcellular_component
GO:0005198Structural molecule activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005911Cell-cell junctionIDAcellular_component
GO:0005915Zonula adherensIEAcellular_component
GO:0007155Cell adhesionIEA NASbiological_process
GO:0007163Establishment or maintenance of cell polarityIEAbiological_process
GO:0007406Negative regulation of neuroblast proliferationIEAbiological_process
GO:0007568AgingIEAbiological_process
GO:0008013Beta-catenin bindingIPImolecular_function
GO:0008584Male gonad developmentIEAbiological_process
GO:0014704Intercalated discIEAcellular_component
GO:0015629Actin cytoskeletonIEAcellular_component
GO:0016264Gap junction assemblyIEAbiological_process
GO:0016342Catenin complexIDAcellular_component
GO:0017166Vinculin bindingIPImolecular_function
GO:0030027LamellipodiumIEAcellular_component
GO:0031103Axon regenerationIEAbiological_process
GO:0034329Cell junction assemblyTASbiological_process
GO:0034332Adherens junction organizationTASbiological_process
GO:0034613Cellular protein localizationIEAbiological_process
GO:0042475Odontogenesis of dentin-containing toothIEAbiological_process
GO:0042692Muscle cell differentiationTASbiological_process
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0043297Apical junction assemblyIEA NASbiological_process
GO:0043627Response to estrogenIEAbiological_process
GO:0045216Cell-cell junction organizationTASbiological_process
GO:0045295Gamma-catenin bindingIPImolecular_function
GO:0045296Cadherin bindingIEA IPImolecular_function
GO:0045880Positive regulation of smoothened signaling pathwayIEAbiological_process
GO:0051015Actin filament bindingIEAmolecular_function
GO:0051149Positive regulation of muscle cell differentiationTASbiological_process
GO:0051291Protein heterooligomerizationIEAbiological_process
GO:0071681Cellular response to indole-3-methanolIDAbiological_process
GO:0090136Epithelial cell-cell adhesionIEAbiological_process
GO:2000146Negative regulation of cell motilityIEAbiological_process
GO:2001045Negative regulation of integrin-mediated signaling pathwayIEAbiological_process
GO:2001240Negative regulation of extrinsic apoptotic signaling pathway in absence of ligandIEAbiological_process
GO:2001241Positive regulation of extrinsic apoptotic signaling pathway in absence of ligandIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.43796126670.49600245430.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1783037685
GSE13712_SHEARUp0.0142207821
GSE13712_STATICDown-0.0260803667
GSE19018Up0.2345525915
GSE19899_A1Down-0.4011898076
GSE19899_A2Up0.1589702601
PubMed_21979375_A1Down-0.0025085243
PubMed_21979375_A2Down-0.7204488507
GSE35957Up0.0306721391
GSE36640Up0.1740432126
GSE54402Down-0.1481388998
GSE9593Up0.4078283124
GSE43922Down-0.0146679591
GSE24585Up0.0424872594
GSE37065Up0.1998485814
GSE28863_A1Up0.3390669156
GSE28863_A2Up0.3157251400
GSE28863_A3Up0.2581604001
GSE28863_A4Down-0.0741836619
GSE48662Down-0.2273245765

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT020722ProteomicsFunctional MTI (Weak)18668040
hsa-miR-744-5pMIMAT0004945MIRT037739CLASHFunctional MTI (Weak)23622248
hsa-miR-296-3pMIMAT0004679MIRT038473CLASHFunctional MTI (Weak)23622248
hsa-miR-769-3pMIMAT0003887MIRT039085CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT039674CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.