HCSGD entry for CTNNA1

1. General information

Official gene symbolCTNNA1
Entrez ID1495
Gene full namecatenin (cadherin-associated protein), alpha 1, 102kDa
Other gene symbolsCAP102
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001541Ovarian follicle developmentIEAbiological_process
GO:0001669Acrosomal vesicleIEAcellular_component
GO:0005198Structural molecule activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005911Cell-cell junctionIDAcellular_component
GO:0005915Zonula adherensIEAcellular_component
GO:0007155Cell adhesionIEA NASbiological_process
GO:0007163Establishment or maintenance of cell polarityIEAbiological_process
GO:0007406Negative regulation of neuroblast proliferationIEAbiological_process
GO:0007568AgingIEAbiological_process
GO:0008013Beta-catenin bindingIPImolecular_function
GO:0008584Male gonad developmentIEAbiological_process
GO:0014704Intercalated discIEAcellular_component
GO:0015629Actin cytoskeletonIEAcellular_component
GO:0016264Gap junction assemblyIEAbiological_process
GO:0016342Catenin complexIDAcellular_component
GO:0017166Vinculin bindingIPImolecular_function
GO:0030027LamellipodiumIEAcellular_component
GO:0031103Axon regenerationIEAbiological_process
GO:0034329Cell junction assemblyTASbiological_process
GO:0034332Adherens junction organizationTASbiological_process
GO:0034613Cellular protein localizationIEAbiological_process
GO:0042475Odontogenesis of dentin-containing toothIEAbiological_process
GO:0042692Muscle cell differentiationTASbiological_process
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0043297Apical junction assemblyIEA NASbiological_process
GO:0043627Response to estrogenIEAbiological_process
GO:0045216Cell-cell junction organizationTASbiological_process
GO:0045295Gamma-catenin bindingIPImolecular_function
GO:0045296Cadherin bindingIEA IPImolecular_function
GO:0045880Positive regulation of smoothened signaling pathwayIEAbiological_process
GO:0051015Actin filament bindingIEAmolecular_function
GO:0051149Positive regulation of muscle cell differentiationTASbiological_process
GO:0051291Protein heterooligomerizationIEAbiological_process
GO:0071681Cellular response to indole-3-methanolIDAbiological_process
GO:0090136Epithelial cell-cell adhesionIEAbiological_process
GO:2000146Negative regulation of cell motilityIEAbiological_process
GO:2001045Negative regulation of integrin-mediated signaling pathwayIEAbiological_process
GO:2001240Negative regulation of extrinsic apoptotic signaling pathway in absence of ligandIEAbiological_process
GO:2001241Positive regulation of extrinsic apoptotic signaling pathway in absence of ligandIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.43796126670.49600245430.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1783037685
GSE13712_SHEARUp0.0142207821
GSE13712_STATICDown-0.0260803667
GSE19018Up0.2345525915
GSE19899_A1Down-0.4011898076
GSE19899_A2Up0.1589702601
PubMed_21979375_A1Down-0.0025085243
PubMed_21979375_A2Down-0.7204488507
GSE35957Up0.0306721391
GSE36640Up0.1740432126
GSE54402Down-0.1481388998
GSE9593Up0.4078283124
GSE43922Down-0.0146679591
GSE24585Up0.0424872594
GSE37065Up0.1998485814
GSE28863_A1Up0.3390669156
GSE28863_A2Up0.3157251400
GSE28863_A3Up0.2581604001
GSE28863_A4Down-0.0741836619
GSE48662Down-0.2273245765

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT020722ProteomicsFunctional MTI (Weak)18668040
hsa-miR-744-5pMIMAT0004945MIRT037739CLASHFunctional MTI (Weak)23622248
hsa-miR-296-3pMIMAT0004679MIRT038473CLASHFunctional MTI (Weak)23622248
hsa-miR-769-3pMIMAT0003887MIRT039085CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT039674CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.