HCSGD entry for CLDN19
1. General information
| Official gene symbol | CLDN19 |
|---|---|
| Entrez ID | 149461 |
| Gene full name | claudin 19 |
| Other gene symbols | HOMG5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005198 | Structural molecule activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005923 | Tight junction | IDA ISS | cellular_component |
| GO:0007601 | Visual perception | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016323 | Basolateral plasma membrane | IDA | cellular_component |
| GO:0016338 | Calcium-independent cell-cell adhesion | ISS | biological_process |
| GO:0019227 | Neuronal action potential propagation | IEA | biological_process |
| GO:0042802 | Identical protein binding | ISS | molecular_function |
| GO:0043296 | Apical junction complex | IDA | cellular_component |
| GO:0043297 | Apical junction assembly | IEA | biological_process |
| GO:0050896 | Response to stimulus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2425298583 | 0.8728189886 | 0.9299221123 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0258049636 |
| GSE13712_SHEAR | Down | -0.0053930770 |
| GSE13712_STATIC | Down | -0.1065125270 |
| GSE19018 | Up | 0.0438872188 |
| GSE19899_A1 | Up | 0.0085502184 |
| GSE19899_A2 | Down | -0.0965654363 |
| PubMed_21979375_A1 | Down | -0.1133281424 |
| PubMed_21979375_A2 | Down | -0.1070629170 |
| GSE35957 | Up | 0.0073383240 |
| GSE36640 | Up | 0.0450675786 |
| GSE54402 | Down | -0.0559580117 |
| GSE9593 | Down | -0.0185905185 |
| GSE43922 | Up | 0.0722506075 |
| GSE24585 | Up | 0.0625739130 |
| GSE37065 | Down | -0.0322627643 |
| GSE28863_A1 | Up | 0.2711416659 |
| GSE28863_A2 | Up | 0.2598699000 |
| GSE28863_A3 | Up | 0.8385446999 |
| GSE28863_A4 | Up | 0.1766170607 |
| GSE48662 | Up | 0.1573651665 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23557734 | The barrier structures of RPE cells were detected by actin-tracker, ZO-1, claudin-19, occludin immunochemistry, and Western blot; barrier function was analyzed by measuring transepithelial resistance (TER) and transepithelial diffusion rate of FITC-dextran |
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