HCSGD entry for CLDN19


1. General information

Official gene symbolCLDN19
Entrez ID149461
Gene full nameclaudin 19
Other gene symbolsHOMG5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005198Structural molecule activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005923Tight junctionIDA ISScellular_component
GO:0007601Visual perceptionIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016323Basolateral plasma membraneIDAcellular_component
GO:0016338Calcium-independent cell-cell adhesionISSbiological_process
GO:0019227Neuronal action potential propagationIEAbiological_process
GO:0042802Identical protein bindingISSmolecular_function
GO:0043296Apical junction complexIDAcellular_component
GO:0043297Apical junction assemblyIEAbiological_process
GO:0050896Response to stimulusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.24252985830.87281898860.92992211231.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0258049636
GSE13712_SHEARDown-0.0053930770
GSE13712_STATICDown-0.1065125270
GSE19018Up0.0438872188
GSE19899_A1Up0.0085502184
GSE19899_A2Down-0.0965654363
PubMed_21979375_A1Down-0.1133281424
PubMed_21979375_A2Down-0.1070629170
GSE35957Up0.0073383240
GSE36640Up0.0450675786
GSE54402Down-0.0559580117
GSE9593Down-0.0185905185
GSE43922Up0.0722506075
GSE24585Up0.0625739130
GSE37065Down-0.0322627643
GSE28863_A1Up0.2711416659
GSE28863_A2Up0.2598699000
GSE28863_A3Up0.8385446999
GSE28863_A4Up0.1766170607
GSE48662Up0.1573651665

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

23557734The barrier structures of RPE cells were detected by actin-tracker, ZO-1, claudin-19, occludin immunochemistry, and Western blot; barrier function was analyzed by measuring transepithelial resistance (TER) and transepithelial diffusion rate of FITC-dextran
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