HCSGD entry for SLC25A10


1. General information

Official gene symbolSLC25A10
Entrez ID1468
Gene full namesolute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
Other gene symbolsDIC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000096Sulfur amino acid metabolic processTASbiological_process
GO:0000098Sulfur amino acid catabolic processTASbiological_process
GO:0003735Structural constituent of ribosomeIEAmolecular_function
GO:0005310Dicarboxylic acid transmembrane transporter activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0005743Mitochondrial inner membraneTAScellular_component
GO:0005840RibosomeIEAcellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0006006Glucose metabolic processTASbiological_process
GO:0006094GluconeogenesisTASbiological_process
GO:0006412TranslationIEAbiological_process
GO:0006810TransportIEAbiological_process
GO:0006811Ion transportTASbiological_process
GO:0006835Dicarboxylic acid transportTASbiological_process
GO:0006839Mitochondrial transportIEAbiological_process
GO:0015114Phosphate ion transmembrane transporter activityIEAmolecular_function
GO:0015116Sulfate transmembrane transporter activityIEAmolecular_function
GO:0015117Thiosulfate transmembrane transporter activityIEAmolecular_function
GO:0015140Malate transmembrane transporter activityIEAmolecular_function
GO:0015141Succinate transmembrane transporter activityIEAmolecular_function
GO:0015297Antiporter activityIEAmolecular_function
GO:0015709Thiosulfate transportIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0031966Mitochondrial membraneIEAcellular_component
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0070221Sulfide oxidation, using sulfide:quinone oxidoreductaseTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.90571970290.12701999920.99999024730.6862260673

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0706691268
GSE13712_SHEARUp0.0092964825
GSE13712_STATICUp0.3289155447
GSE19018Down-0.1944240609
GSE19899_A1Down-0.2549820598
GSE19899_A2Up0.1554407089
PubMed_21979375_A1Up0.2503660837
PubMed_21979375_A2Down-0.1775254006
GSE35957Down-0.3199284424
GSE36640Down-0.2131177737
GSE54402Up0.1062822518
GSE9593Down-0.7526690158
GSE43922Up0.0840969833
GSE24585Down-0.1097843621
GSE37065Down-0.2348663206
GSE28863_A1Down-0.2060999356
GSE28863_A2Down-0.0186386065
GSE28863_A3Down-0.0711010915
GSE28863_A4Up0.1508414374
GSE48662Down-0.3464757572

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT023781ProteomicsFunctional MTI (Weak)18668040
hsa-miR-193b-3pMIMAT0002819MIRT041535CLASHFunctional MTI (Weak)23622248
hsa-miR-222-3pMIMAT0000279MIRT046668CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

19484468Images of human erythrocytes from a healthy donor were recorded under differential interference contrast (DIC) microscopy; they were acquired rapidly (approximately 336 Hz) and the intensity of the centermost pixel of each cell was recorded for approximately 60 s (20,000 values)
1635178Initial response was observed as correction of DIC within a week of treatment
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