HCSGD entry for SLC25A10
1. General information
| Official gene symbol | SLC25A10 |
|---|---|
| Entrez ID | 1468 |
| Gene full name | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| Other gene symbols | DIC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000096 | Sulfur amino acid metabolic process | TAS | biological_process |
| GO:0000098 | Sulfur amino acid catabolic process | TAS | biological_process |
| GO:0003735 | Structural constituent of ribosome | IEA | molecular_function |
| GO:0005310 | Dicarboxylic acid transmembrane transporter activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | TAS | cellular_component |
| GO:0005840 | Ribosome | IEA | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006006 | Glucose metabolic process | TAS | biological_process |
| GO:0006094 | Gluconeogenesis | TAS | biological_process |
| GO:0006412 | Translation | IEA | biological_process |
| GO:0006810 | Transport | IEA | biological_process |
| GO:0006811 | Ion transport | TAS | biological_process |
| GO:0006835 | Dicarboxylic acid transport | TAS | biological_process |
| GO:0006839 | Mitochondrial transport | IEA | biological_process |
| GO:0015114 | Phosphate ion transmembrane transporter activity | IEA | molecular_function |
| GO:0015116 | Sulfate transmembrane transporter activity | IEA | molecular_function |
| GO:0015117 | Thiosulfate transmembrane transporter activity | IEA | molecular_function |
| GO:0015140 | Malate transmembrane transporter activity | IEA | molecular_function |
| GO:0015141 | Succinate transmembrane transporter activity | IEA | molecular_function |
| GO:0015297 | Antiporter activity | IEA | molecular_function |
| GO:0015709 | Thiosulfate transport | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0031966 | Mitochondrial membrane | IEA | cellular_component |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:0070221 | Sulfide oxidation, using sulfide:quinone oxidoreductase | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9057197029 | 0.1270199992 | 0.9999902473 | 0.6862260673 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0706691268 |
| GSE13712_SHEAR | Up | 0.0092964825 |
| GSE13712_STATIC | Up | 0.3289155447 |
| GSE19018 | Down | -0.1944240609 |
| GSE19899_A1 | Down | -0.2549820598 |
| GSE19899_A2 | Up | 0.1554407089 |
| PubMed_21979375_A1 | Up | 0.2503660837 |
| PubMed_21979375_A2 | Down | -0.1775254006 |
| GSE35957 | Down | -0.3199284424 |
| GSE36640 | Down | -0.2131177737 |
| GSE54402 | Up | 0.1062822518 |
| GSE9593 | Down | -0.7526690158 |
| GSE43922 | Up | 0.0840969833 |
| GSE24585 | Down | -0.1097843621 |
| GSE37065 | Down | -0.2348663206 |
| GSE28863_A1 | Down | -0.2060999356 |
| GSE28863_A2 | Down | -0.0186386065 |
| GSE28863_A3 | Down | -0.0711010915 |
| GSE28863_A4 | Up | 0.1508414374 |
| GSE48662 | Down | -0.3464757572 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023781 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041535 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046668 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 19484468 | Images of human erythrocytes from a healthy donor were recorded under differential interference contrast (DIC) microscopy; they were acquired rapidly (approximately 336 Hz) and the intensity of the centermost pixel of each cell was recorded for approximately 60 s (20,000 values) |
| 1635178 | Initial response was observed as correction of DIC within a week of treatment |
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