HCSGD entry for CRY2

1. General information

Official gene symbolCRY2
Entrez ID1408
Gene full namecryptochrome 2 (photolyase-like)
Other gene symbolsHCRY2 PHLL2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0000719Photoreactive repairIDAbiological_process
GO:0000989Transcription factor binding transcription factor activityIDAmolecular_function
GO:0003677DNA bindingIDAmolecular_function
GO:0003684Damaged DNA bindingIDAmolecular_function
GO:0003697Single-stranded DNA bindingIDAmolecular_function
GO:0003904Deoxyribodipyrimidine photo-lyase activityIDAmolecular_function
GO:0003913DNA photolyase activityIEAmolecular_function
GO:0003914DNA (6-4) photolyase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIDAcellular_component
GO:0005634NucleusIDA ISScellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0006281DNA repairIEAbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006606Protein import into nucleusIEAbiological_process
GO:0007623Circadian rhythmIEA ISSbiological_process
GO:0009785Blue light signaling pathwayNASbiological_process
GO:0009882Blue light photoreceptor activityNASmolecular_function
GO:0018298Protein-chromophore linkageIEAbiological_process
GO:0019901Protein kinase bindingIEAmolecular_function
GO:0019902Phosphatase bindingIPImolecular_function
GO:0032515Negative regulation of phosphoprotein phosphatase activityIDAbiological_process
GO:0042752Regulation of circadian rhythmIEAbiological_process
GO:0071949FAD bindingIEA ISSmolecular_function
GO:2000118Regulation of sodium-dependent phosphate transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.22702844500.77162960370.90850022801.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1088010345
GSE13712_SHEARDown-0.5100448603
GSE13712_STATICUp0.0388242616
GSE19018Up0.2215699271
GSE19899_A1Down-0.1642650129
GSE19899_A2Up0.0288394691
PubMed_21979375_A1Up0.1385387076
PubMed_21979375_A2Up0.4424310769
GSE35957Up0.1300433160
GSE36640Up1.1797051589
GSE54402Down-0.2403786742
GSE9593Up0.0153263721
GSE43922Up0.0504102472
GSE24585Up0.0557261414
GSE37065Up0.0356963588
GSE28863_A1Up0.2967075371
GSE28863_A2Up0.0708268159
GSE28863_A3Down-0.1864145694
GSE28863_A4Down-0.0659730166
GSE48662Up0.3082701582

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-340-5pMIMAT0004692MIRT019611SequencingFunctional MTI (Weak)20371350
hsa-miR-130b-3pMIMAT0000691MIRT020147SequencingFunctional MTI (Weak)20371350
hsa-miR-93-5pMIMAT0000093MIRT028006SequencingFunctional MTI (Weak)20371350
hsa-miR-33a-5pMIMAT0000091MIRT028213SequencingFunctional MTI (Weak)20371350
hsa-miR-532-3pMIMAT0004780MIRT037929CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.