HCSGD entry for CRY2
1. General information
Official gene symbol | CRY2 |
---|---|
Entrez ID | 1408 |
Gene full name | cryptochrome 2 (photolyase-like) |
Other gene symbols | HCRY2 PHLL2 |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
GO:0000719 | Photoreactive repair | IDA | biological_process |
GO:0000989 | Transcription factor binding transcription factor activity | IDA | molecular_function |
GO:0003677 | DNA binding | IDA | molecular_function |
GO:0003684 | Damaged DNA binding | IDA | molecular_function |
GO:0003697 | Single-stranded DNA binding | IDA | molecular_function |
GO:0003904 | Deoxyribodipyrimidine photo-lyase activity | IDA | molecular_function |
GO:0003913 | DNA photolyase activity | IEA | molecular_function |
GO:0003914 | DNA (6-4) photolyase activity | IDA | molecular_function |
GO:0005515 | Protein binding | IPI | molecular_function |
GO:0005576 | Extracellular region | IDA | cellular_component |
GO:0005634 | Nucleus | IDA ISS | cellular_component |
GO:0005737 | Cytoplasm | IDA | cellular_component |
GO:0005739 | Mitochondrion | IEA | cellular_component |
GO:0006281 | DNA repair | IEA | biological_process |
GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
GO:0006606 | Protein import into nucleus | IEA | biological_process |
GO:0007623 | Circadian rhythm | IEA ISS | biological_process |
GO:0009785 | Blue light signaling pathway | NAS | biological_process |
GO:0009882 | Blue light photoreceptor activity | NAS | molecular_function |
GO:0018298 | Protein-chromophore linkage | IEA | biological_process |
GO:0019901 | Protein kinase binding | IEA | molecular_function |
GO:0019902 | Phosphatase binding | IPI | molecular_function |
GO:0032515 | Negative regulation of phosphoprotein phosphatase activity | IDA | biological_process |
GO:0042752 | Regulation of circadian rhythm | IEA | biological_process |
GO:0071949 | FAD binding | IEA ISS | molecular_function |
GO:2000118 | Regulation of sodium-dependent phosphate transport | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.2270284450 | 0.7716296037 | 0.9085002280 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Up | 0.1088010345 |
GSE13712_SHEAR | Down | -0.5100448603 |
GSE13712_STATIC | Up | 0.0388242616 |
GSE19018 | Up | 0.2215699271 |
GSE19899_A1 | Down | -0.1642650129 |
GSE19899_A2 | Up | 0.0288394691 |
PubMed_21979375_A1 | Up | 0.1385387076 |
PubMed_21979375_A2 | Up | 0.4424310769 |
GSE35957 | Up | 0.1300433160 |
GSE36640 | Up | 1.1797051589 |
GSE54402 | Down | -0.2403786742 |
GSE9593 | Up | 0.0153263721 |
GSE43922 | Up | 0.0504102472 |
GSE24585 | Up | 0.0557261414 |
GSE37065 | Up | 0.0356963588 |
GSE28863_A1 | Up | 0.2967075371 |
GSE28863_A2 | Up | 0.0708268159 |
GSE28863_A3 | Down | -0.1864145694 |
GSE28863_A4 | Down | -0.0659730166 |
GSE48662 | Up | 0.3082701582 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-340-5p | MIMAT0004692 | MIRT019611 | Sequencing | Functional MTI (Weak) | 20371350 |
hsa-miR-130b-3p | MIMAT0000691 | MIRT020147 | Sequencing | Functional MTI (Weak) | 20371350 |
hsa-miR-93-5p | MIMAT0000093 | MIRT028006 | Sequencing | Functional MTI (Weak) | 20371350 |
hsa-miR-33a-5p | MIMAT0000091 | MIRT028213 | Sequencing | Functional MTI (Weak) | 20371350 |
hsa-miR-532-3p | MIMAT0004780 | MIRT037929 | CLASH | Functional MTI (Weak) | 23622248 |
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