HCSGD entry for CLDN4


1. General information

Official gene symbolCLDN4
Entrez ID1364
Gene full nameclaudin 4
Other gene symbolsCPE-R CPER CPETR CPETR1 WBSCR8 hCPE-R
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004888Transmembrane signaling receptor activityTASmolecular_function
GO:0005198Structural molecule activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0005923Tight junctionISScellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007565Female pregnancyIEAbiological_process
GO:0009925Basal plasma membraneIEAcellular_component
GO:0016324Apical plasma membraneIEAcellular_component
GO:0016327Apicolateral plasma membraneIEAcellular_component
GO:0016328Lateral plasma membraneIEAcellular_component
GO:0016338Calcium-independent cell-cell adhesionISSbiological_process
GO:0032570Response to progesteroneIEAbiological_process
GO:0042802Identical protein bindingISSmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.40967956000.86419262190.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0084450132
GSE13712_SHEARUp0.0634566180
GSE13712_STATICDown-0.0043750526
GSE19018Up0.0457721286
GSE19899_A1Up0.0067058943
GSE19899_A2Up0.0750192036
PubMed_21979375_A1Down-0.1354456032
PubMed_21979375_A2Down-0.2273748129
GSE35957Up0.1562843822
GSE36640Down-0.2070837817
GSE54402Up0.4004943186
GSE9593Up0.0399771993
GSE43922Up0.0254894702
GSE24585Up0.4841505205
GSE37065Up0.0009113702
GSE28863_A1Down-0.0759914840
GSE28863_A2Up0.1328559374
GSE28863_A3Up0.0409230862
GSE28863_A4Up0.1360850464
GSE48662Up0.0815479844

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017395MicroarrayFunctional MTI (Weak)18185580
hsa-let-7e-5pMIMAT0000066MIRT051675CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.