HCSGD entry for CLDN4
1. General information
| Official gene symbol | CLDN4 |
|---|---|
| Entrez ID | 1364 |
| Gene full name | claudin 4 |
| Other gene symbols | CPE-R CPER CPETR CPETR1 WBSCR8 hCPE-R |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004888 | Transmembrane signaling receptor activity | TAS | molecular_function |
| GO:0005198 | Structural molecule activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0005923 | Tight junction | ISS | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007565 | Female pregnancy | IEA | biological_process |
| GO:0009925 | Basal plasma membrane | IEA | cellular_component |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0016327 | Apicolateral plasma membrane | IEA | cellular_component |
| GO:0016328 | Lateral plasma membrane | IEA | cellular_component |
| GO:0016338 | Calcium-independent cell-cell adhesion | ISS | biological_process |
| GO:0032570 | Response to progesterone | IEA | biological_process |
| GO:0042802 | Identical protein binding | ISS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4096795600 | 0.8641926219 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0084450132 |
| GSE13712_SHEAR | Up | 0.0634566180 |
| GSE13712_STATIC | Down | -0.0043750526 |
| GSE19018 | Up | 0.0457721286 |
| GSE19899_A1 | Up | 0.0067058943 |
| GSE19899_A2 | Up | 0.0750192036 |
| PubMed_21979375_A1 | Down | -0.1354456032 |
| PubMed_21979375_A2 | Down | -0.2273748129 |
| GSE35957 | Up | 0.1562843822 |
| GSE36640 | Down | -0.2070837817 |
| GSE54402 | Up | 0.4004943186 |
| GSE9593 | Up | 0.0399771993 |
| GSE43922 | Up | 0.0254894702 |
| GSE24585 | Up | 0.4841505205 |
| GSE37065 | Up | 0.0009113702 |
| GSE28863_A1 | Down | -0.0759914840 |
| GSE28863_A2 | Up | 0.1328559374 |
| GSE28863_A3 | Up | 0.0409230862 |
| GSE28863_A4 | Up | 0.1360850464 |
| GSE48662 | Up | 0.0815479844 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017395 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051675 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
