HCSGD entry for COX10
1. General information
| Official gene symbol | COX10 |
|---|---|
| Entrez ID | 1352 |
| Gene full name | cytochrome c oxidase assembly homolog 10 (yeast) |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000266 | Mitochondrial fission | IEA | biological_process |
| GO:0004129 | Cytochrome-c oxidase activity | IMP | molecular_function |
| GO:0004311 | Farnesyltranstransferase activity | TAS | molecular_function |
| GO:0005739 | Mitochondrion | IC IEA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | TAS | cellular_component |
| GO:0006123 | Mitochondrial electron transport, cytochrome c to oxygen | IC | biological_process |
| GO:0006778 | Porphyrin-containing compound metabolic process | TAS | biological_process |
| GO:0006783 | Heme biosynthetic process | TAS | biological_process |
| GO:0006784 | Heme a biosynthetic process | IEA IMP | biological_process |
| GO:0006810 | Transport | IMP | biological_process |
| GO:0006812 | Cation transport | IMP | biological_process |
| GO:0008495 | Protoheme IX farnesyltransferase activity | IEA | molecular_function |
| GO:0008535 | Respiratory chain complex IV assembly | IMP | biological_process |
| GO:0009060 | Aerobic respiration | IEA | biological_process |
| GO:0015672 | Monovalent inorganic cation transport | IMP | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0017004 | Cytochrome complex assembly | IEA | biological_process |
| GO:0034220 | Ion transmembrane transport | IMP | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045333 | Cellular respiration | IGI | biological_process |
| GO:0048034 | Heme O biosynthetic process | IEA | biological_process |
| GO:0055085 | Transmembrane transport | IMP | biological_process |
| GO:1902600 | Hydrogen ion transmembrane transport | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6365697162 | 0.4997046807 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2005291751 |
| GSE13712_SHEAR | Up | 0.1322214566 |
| GSE13712_STATIC | Up | 0.0341855391 |
| GSE19018 | Down | -0.1020073919 |
| GSE19899_A1 | Down | -0.0350110801 |
| GSE19899_A2 | Up | 0.4440641349 |
| PubMed_21979375_A1 | Up | 0.4479295737 |
| PubMed_21979375_A2 | Up | 0.5694743561 |
| GSE35957 | Up | 0.0021169023 |
| GSE36640 | Down | -0.1101174696 |
| GSE54402 | Up | 0.0008138127 |
| GSE9593 | Down | -0.1850108632 |
| GSE43922 | Up | 0.0534128966 |
| GSE24585 | Down | -0.0730252343 |
| GSE37065 | Up | 0.0217014692 |
| GSE28863_A1 | Down | -0.1433393551 |
| GSE28863_A2 | Down | -0.5308424008 |
| GSE28863_A3 | Down | -0.2486366979 |
| GSE28863_A4 | Down | -0.0003714836 |
| GSE48662 | Down | -0.1658322421 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020193 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027567 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031141 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051700 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
