HCSGD entry for COX10


1. General information

Official gene symbolCOX10
Entrez ID1352
Gene full namecytochrome c oxidase assembly homolog 10 (yeast)
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000266Mitochondrial fissionIEAbiological_process
GO:0004129Cytochrome-c oxidase activityIMPmolecular_function
GO:0004311Farnesyltranstransferase activityTASmolecular_function
GO:0005739MitochondrionIC IEAcellular_component
GO:0005743Mitochondrial inner membraneTAScellular_component
GO:0006123Mitochondrial electron transport, cytochrome c to oxygenICbiological_process
GO:0006778Porphyrin-containing compound metabolic processTASbiological_process
GO:0006783Heme biosynthetic processTASbiological_process
GO:0006784Heme a biosynthetic processIEA IMPbiological_process
GO:0006810TransportIMPbiological_process
GO:0006812Cation transportIMPbiological_process
GO:0008495Protoheme IX farnesyltransferase activityIEAmolecular_function
GO:0008535Respiratory chain complex IV assemblyIMPbiological_process
GO:0009060Aerobic respirationIEAbiological_process
GO:0015672Monovalent inorganic cation transportIMPbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0017004Cytochrome complex assemblyIEAbiological_process
GO:0034220Ion transmembrane transportIMPbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045333Cellular respirationIGIbiological_process
GO:0048034Heme O biosynthetic processIEAbiological_process
GO:0055085Transmembrane transportIMPbiological_process
GO:1902600Hydrogen ion transmembrane transportIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.63656971620.49970468070.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2005291751
GSE13712_SHEARUp0.1322214566
GSE13712_STATICUp0.0341855391
GSE19018Down-0.1020073919
GSE19899_A1Down-0.0350110801
GSE19899_A2Up0.4440641349
PubMed_21979375_A1Up0.4479295737
PubMed_21979375_A2Up0.5694743561
GSE35957Up0.0021169023
GSE36640Down-0.1101174696
GSE54402Up0.0008138127
GSE9593Down-0.1850108632
GSE43922Up0.0534128966
GSE24585Down-0.0730252343
GSE37065Up0.0217014692
GSE28863_A1Down-0.1433393551
GSE28863_A2Down-0.5308424008
GSE28863_A3Down-0.2486366979
GSE28863_A4Down-0.0003714836
GSE48662Down-0.1658322421

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-130b-3pMIMAT0000691MIRT020193SequencingFunctional MTI (Weak)20371350
hsa-miR-98-5pMIMAT0000096MIRT027567MicroarrayFunctional MTI (Weak)19088304
hsa-miR-19b-3pMIMAT0000074MIRT031141SequencingFunctional MTI (Weak)20371350
hsa-let-7e-5pMIMAT0000066MIRT051700CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.