HCSGD entry for CMKLR1

1. General information

Official gene symbolCMKLR1
Entrez ID1240
Gene full namechemokine-like receptor 1
Other gene symbolsCHEMERINR ChemR23 DEZ RVER1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001501Skeletal system developmentTASbiological_process
GO:0004872Receptor activityTASmolecular_function
GO:0004930G-protein coupled receptor activityNASmolecular_function
GO:0004950Chemokine receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneIDAcellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006935ChemotaxisIDA IEAbiological_process
GO:0006955Immune responseTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIDA NASbiological_process
GO:0010759Positive regulation of macrophage chemotaxisIMPbiological_process
GO:0016021Integral component of membraneIEA NAScellular_component
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0032088Negative regulation of NF-kappaB transcription factor activityIDAbiological_process
GO:0032695Negative regulation of interleukin-12 productionIEA ISSbiological_process
GO:0045600Positive regulation of fat cell differentiationISSbiological_process
GO:0050848Regulation of calcium-mediated signalingIDAbiological_process
GO:0070098Chemokine-mediated signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03740281140.38760974130.43640155141.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0296124786
GSE13712_SHEARDown-3.3028591780
GSE13712_STATICUp0.1096528109
GSE19018Up0.1028338214
GSE19899_A1Up0.0973030617
GSE19899_A2Up0.0517528188
PubMed_21979375_A1Down-0.1785824120
PubMed_21979375_A2Down-0.0836708234
GSE35957Down-1.0497960924
GSE36640Up0.0851596463
GSE54402Up0.0431064511
GSE9593Up0.2453711550
GSE43922Up0.2766928338
GSE24585Up0.1501245976
GSE37065Up0.2865016492
GSE28863_A1Up0.5330050913
GSE28863_A2Up1.2922005732
GSE28863_A3Up0.1267556387
GSE28863_A4Up0.4396383867
GSE48662Up0.5932218026

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.