HCSGD entry for CMKLR1

1. General information

Official gene symbolCMKLR1
Entrez ID1240
Gene full namechemokine-like receptor 1
Other gene symbolsCHEMERINR ChemR23 DEZ RVER1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001501Skeletal system developmentTASbiological_process
GO:0004872Receptor activityTASmolecular_function
GO:0004930G-protein coupled receptor activityNASmolecular_function
GO:0004950Chemokine receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneIDAcellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006935ChemotaxisIDA IEAbiological_process
GO:0006955Immune responseTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIDA NASbiological_process
GO:0010759Positive regulation of macrophage chemotaxisIMPbiological_process
GO:0016021Integral component of membraneIEA NAScellular_component
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0032088Negative regulation of NF-kappaB transcription factor activityIDAbiological_process
GO:0032695Negative regulation of interleukin-12 productionIEA ISSbiological_process
GO:0045600Positive regulation of fat cell differentiationISSbiological_process
GO:0050848Regulation of calcium-mediated signalingIDAbiological_process
GO:0070098Chemokine-mediated signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03740281140.38760974130.43640155141.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0296124786
GSE13712_SHEARDown-3.3028591780
GSE13712_STATICUp0.1096528109
GSE19018Up0.1028338214
GSE19899_A1Up0.0973030617
GSE19899_A2Up0.0517528188
PubMed_21979375_A1Down-0.1785824120
PubMed_21979375_A2Down-0.0836708234
GSE35957Down-1.0497960924
GSE36640Up0.0851596463
GSE54402Up0.0431064511
GSE9593Up0.2453711550
GSE43922Up0.2766928338
GSE24585Up0.1501245976
GSE37065Up0.2865016492
GSE28863_A1Up0.5330050913
GSE28863_A2Up1.2922005732
GSE28863_A3Up0.1267556387
GSE28863_A4Up0.4396383867
GSE48662Up0.5932218026

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.