HCSGD entry for ADD3
1. General information
| Official gene symbol | ADD3 |
|---|---|
| Entrez ID | 120 |
| Gene full name | adducin 3 (gamma) |
| Other gene symbols | ADDL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000794 | Condensed nuclear chromosome | IEA | cellular_component |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005200 | Structural constituent of cytoskeleton | TAS | molecular_function |
| GO:0005516 | Calmodulin binding | IEA | molecular_function |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0005911 | Cell-cell junction | IEA | cellular_component |
| GO:0005938 | Cell cortex | IEA | cellular_component |
| GO:0016020 | Membrane | TAS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0962109532 | 0.0314714980 | 0.6491022222 | 0.3330202410 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.7237701922 |
| GSE13712_SHEAR | Down | -1.8168353373 |
| GSE13712_STATIC | Down | -1.1794433672 |
| GSE19018 | Up | 0.8583438263 |
| GSE19899_A1 | Up | 0.0654199259 |
| GSE19899_A2 | Down | -0.6638592598 |
| PubMed_21979375_A1 | Down | -1.6468603534 |
| PubMed_21979375_A2 | Down | -1.0143755353 |
| GSE35957 | Up | 0.1637883746 |
| GSE36640 | Down | -0.0587284537 |
| GSE54402 | Down | -0.0279834400 |
| GSE9593 | Up | 0.5160110219 |
| GSE43922 | Down | -0.1833923057 |
| GSE24585 | Up | 0.3146238013 |
| GSE37065 | Up | 0.2226311645 |
| GSE28863_A1 | Up | 0.5954946398 |
| GSE28863_A2 | Up | 0.3329536290 |
| GSE28863_A3 | Down | -1.0161571091 |
| GSE28863_A4 | Up | 0.2248377538 |
| GSE48662 | Down | -0.0959261611 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-374b-5p | MIMAT0004955 | MIRT016076 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022859 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030536 | Microarray | Functional MTI (Weak) | 19748357 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
