HCSGD entry for ADD3


1. General information

Official gene symbolADD3
Entrez ID120
Gene full nameadducin 3 (gamma)
Other gene symbolsADDL
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000794Condensed nuclear chromosomeIEAcellular_component
GO:0003779Actin bindingIEAmolecular_function
GO:0005200Structural constituent of cytoskeletonTASmolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005856CytoskeletonIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0005911Cell-cell junctionIEAcellular_component
GO:0005938Cell cortexIEAcellular_component
GO:0016020MembraneTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09621095320.03147149800.64910222220.3330202410

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.7237701922
GSE13712_SHEARDown-1.8168353373
GSE13712_STATICDown-1.1794433672
GSE19018Up0.8583438263
GSE19899_A1Up0.0654199259
GSE19899_A2Down-0.6638592598
PubMed_21979375_A1Down-1.6468603534
PubMed_21979375_A2Down-1.0143755353
GSE35957Up0.1637883746
GSE36640Down-0.0587284537
GSE54402Down-0.0279834400
GSE9593Up0.5160110219
GSE43922Down-0.1833923057
GSE24585Up0.3146238013
GSE37065Up0.2226311645
GSE28863_A1Up0.5954946398
GSE28863_A2Up0.3329536290
GSE28863_A3Down-1.0161571091
GSE28863_A4Up0.2248377538
GSE48662Down-0.0959261611

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-374b-5pMIMAT0004955MIRT016076SequencingFunctional MTI (Weak)20371350
hsa-miR-124-3pMIMAT0000422MIRT022859Proteomics;MicroarrayFunctional MTI (Weak)18668037
hsa-miR-24-3pMIMAT0000080MIRT030536MicroarrayFunctional MTI (Weak)19748357
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.