HCSGD entry for CLC


1. General information

Official gene symbolCLC
Entrez ID1178
Gene full nameCharcot-Leyden crystal protein
Other gene symbolsGAL10 Gal-10 LGALS10 LGALS10A LPPL_HUMAN
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002667Regulation of T cell anergyIMPbiological_process
GO:0002724Regulation of T cell cytokine productionIMPbiological_process
GO:0004622Lysophospholipase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolIDAcellular_component
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0008152Metabolic processIDAbiological_process
GO:0030246Carbohydrate bindingIEAmolecular_function
GO:0046006Regulation of activated T cell proliferationIMPbiological_process
GO:0070231T cell apoptotic processIDAbiological_process
GO:0097153Cysteine-type endopeptidase activity involved in apoptotic processIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.70439259910.80371214620.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0204414505
GSE13712_SHEARDown-0.2361496239
GSE13712_STATICDown-0.0085723461
GSE19018Up0.1862476685
GSE19899_A1Up0.0261502131
GSE19899_A2Up0.1185296075
PubMed_21979375_A1Up0.0561473454
PubMed_21979375_A2Down-0.3396307717
GSE35957Up0.0491110202
GSE36640Down-0.0207013827
GSE54402Down-0.0433242619
GSE9593Up0.0522090020
GSE43922Up0.0382461115
GSE24585Up0.0373917437
GSE37065Up0.1231648848
GSE28863_A1Up0.0889803331
GSE28863_A2Down-0.0430041203
GSE28863_A3Up0.1977403589
GSE28863_A4Up0.0740048029
GSE48662Down-0.0123802967

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

N-EthylmaleimideDB02967 EXPT02327
Para-Mercury-Benzenesulfonic AcidDB02983 EXPT02614

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.