HCSGD entry for CLC


1. General information

Official gene symbolCLC
Entrez ID1178
Gene full nameCharcot-Leyden crystal protein
Other gene symbolsGAL10 Gal-10 LGALS10 LGALS10A LPPL_HUMAN
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002667Regulation of T cell anergyIMPbiological_process
GO:0002724Regulation of T cell cytokine productionIMPbiological_process
GO:0004622Lysophospholipase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolIDAcellular_component
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0008152Metabolic processIDAbiological_process
GO:0030246Carbohydrate bindingIEAmolecular_function
GO:0046006Regulation of activated T cell proliferationIMPbiological_process
GO:0070231T cell apoptotic processIDAbiological_process
GO:0097153Cysteine-type endopeptidase activity involved in apoptotic processIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.70439259910.80371214620.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0204414505
GSE13712_SHEARDown-0.2361496239
GSE13712_STATICDown-0.0085723461
GSE19018Up0.1862476685
GSE19899_A1Up0.0261502131
GSE19899_A2Up0.1185296075
PubMed_21979375_A1Up0.0561473454
PubMed_21979375_A2Down-0.3396307717
GSE35957Up0.0491110202
GSE36640Down-0.0207013827
GSE54402Down-0.0433242619
GSE9593Up0.0522090020
GSE43922Up0.0382461115
GSE24585Up0.0373917437
GSE37065Up0.1231648848
GSE28863_A1Up0.0889803331
GSE28863_A2Down-0.0430041203
GSE28863_A3Up0.1977403589
GSE28863_A4Up0.0740048029
GSE48662Down-0.0123802967

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

N-EthylmaleimideDB02967 EXPT02327
Para-Mercury-Benzenesulfonic AcidDB02983 EXPT02614

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.