HCSGD entry for AP2S1

1. General information

Official gene symbolAP2S1
Entrez ID1175
Gene full nameadaptor-related protein complex 2, sigma 1 subunit
Other gene symbolsAP17 AP17-DELTA CLAPS2 HHC3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005215Transporter activityNASmolecular_function
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006886Intracellular protein transportIEAbiological_process
GO:0006897EndocytosisIEAbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0008565Protein transporter activityIEA NASmolecular_function
GO:0016032Viral processTASbiological_process
GO:0016192Vesicle-mediated transportIEAbiological_process
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IITASbiological_process
GO:0030100Regulation of endocytosisTASbiological_process
GO:0030117Membrane coatIEAcellular_component
GO:0030122AP-2 adaptor complexIEA TAScellular_component
GO:0030666Endocytic vesicle membraneTAScellular_component
GO:0030669Clathrin-coated endocytic vesicle membraneTAScellular_component
GO:0042059Negative regulation of epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0048268Clathrin coat assemblyTASbiological_process
GO:0050690Regulation of defense response to virus by virusTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04996025990.53668321110.48963916761.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0867657837
GSE13712_SHEARDown-0.0541228347
GSE13712_STATICUp0.0352856433
GSE19018Up0.4417783310
GSE19899_A1Up0.2201548683
GSE19899_A2Up0.7653110671
PubMed_21979375_A1Up1.6761113176
PubMed_21979375_A2Up0.3596242746
GSE35957Down-0.1656345981
GSE36640Up0.3387398377
GSE54402Up0.7228648935
GSE9593Up0.1472106799
GSE43922Up0.3171587501
GSE24585Down-0.3505322106
GSE37065Down-0.3199800572
GSE28863_A1Down-0.4473511131
GSE28863_A2Down-0.7910901050
GSE28863_A3Down-0.1727066431
GSE28863_A4Up0.2380478474
GSE48662Down-0.0177858827

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT023500ProteomicsFunctional MTI (Weak)18668040
hsa-miR-30a-5pMIMAT0000087MIRT028446ProteomicsFunctional MTI (Weak)18668040
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.