HCSGD entry for AP2S1

1. General information

Official gene symbolAP2S1
Entrez ID1175
Gene full nameadaptor-related protein complex 2, sigma 1 subunit
Other gene symbolsAP17 AP17-DELTA CLAPS2 HHC3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005215Transporter activityNASmolecular_function
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006886Intracellular protein transportIEAbiological_process
GO:0006897EndocytosisIEAbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0008565Protein transporter activityIEA NASmolecular_function
GO:0016032Viral processTASbiological_process
GO:0016192Vesicle-mediated transportIEAbiological_process
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IITASbiological_process
GO:0030100Regulation of endocytosisTASbiological_process
GO:0030117Membrane coatIEAcellular_component
GO:0030122AP-2 adaptor complexIEA TAScellular_component
GO:0030666Endocytic vesicle membraneTAScellular_component
GO:0030669Clathrin-coated endocytic vesicle membraneTAScellular_component
GO:0042059Negative regulation of epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0048268Clathrin coat assemblyTASbiological_process
GO:0050690Regulation of defense response to virus by virusTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04996025990.53668321110.48963916761.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0867657837
GSE13712_SHEARDown-0.0541228347
GSE13712_STATICUp0.0352856433
GSE19018Up0.4417783310
GSE19899_A1Up0.2201548683
GSE19899_A2Up0.7653110671
PubMed_21979375_A1Up1.6761113176
PubMed_21979375_A2Up0.3596242746
GSE35957Down-0.1656345981
GSE36640Up0.3387398377
GSE54402Up0.7228648935
GSE9593Up0.1472106799
GSE43922Up0.3171587501
GSE24585Down-0.3505322106
GSE37065Down-0.3199800572
GSE28863_A1Down-0.4473511131
GSE28863_A2Down-0.7910901050
GSE28863_A3Down-0.1727066431
GSE28863_A4Up0.2380478474
GSE48662Down-0.0177858827

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT023500ProteomicsFunctional MTI (Weak)18668040
hsa-miR-30a-5pMIMAT0000087MIRT028446ProteomicsFunctional MTI (Weak)18668040
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.