HCSGD entry for ADCY8
1. General information
| Official gene symbol | ADCY8 |
|---|---|
| Entrez ID | 114 |
| Gene full name | adenylate cyclase 8 (brain) |
| Other gene symbols | AC8 ADCY3 HBAC1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0004016 | Adenylate cyclase activity | IEA TAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006112 | Energy reserve metabolic process | TAS | biological_process |
| GO:0006833 | Water transport | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007173 | Epidermal growth factor receptor signaling pathway | TAS | biological_process |
| GO:0007189 | Adenylate cyclase-activating G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007193 | Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007202 | Activation of phospholipase C activity | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0007611 | Learning or memory | TAS | biological_process |
| GO:0007616 | Long-term memory | IEA | biological_process |
| GO:0008294 | Calcium- and calmodulin-responsive adenylate cyclase activity | TAS | molecular_function |
| GO:0008543 | Fibroblast growth factor receptor signaling pathway | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0034199 | Activation of protein kinase A activity | TAS | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048011 | Neurotrophin TRK receptor signaling pathway | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:0071377 | Cellular response to glucagon stimulus | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6660277155 | 0.9105194066 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0326474492 |
| GSE13712_SHEAR | Down | -0.1479375210 |
| GSE13712_STATIC | Down | -0.0337811345 |
| GSE19018 | Down | -0.0348134407 |
| GSE19899_A1 | Up | 0.0590597737 |
| GSE19899_A2 | Up | 0.1105542906 |
| PubMed_21979375_A1 | Up | 0.1133103812 |
| PubMed_21979375_A2 | Down | -0.0704387042 |
| GSE35957 | Down | -0.1056972766 |
| GSE36640 | Up | 0.0532011953 |
| GSE54402 | Up | 0.2272258185 |
| GSE9593 | Down | -0.0241112032 |
| GSE43922 | Up | 0.0146001632 |
| GSE24585 | Up | 0.2569715802 |
| GSE37065 | Up | 0.0484597164 |
| GSE28863_A1 | Up | 0.0029418936 |
| GSE28863_A2 | Up | 0.0115902174 |
| GSE28863_A3 | Up | 0.1629673891 |
| GSE28863_A4 | Up | 0.0799659833 |
| GSE48662 | Up | 0.0478834271 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
