HCSGD entry for ADCY8

1. General information

Official gene symbolADCY8
Entrez ID114
Gene full nameadenylate cyclase 8 (brain)
Other gene symbolsAC8 ADCY3 HBAC1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0004016Adenylate cyclase activityIEA TASmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0006833Water transportTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0007189Adenylate cyclase-activating G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007193Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007202Activation of phospholipase C activityTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007611Learning or memoryTASbiological_process
GO:0007616Long-term memoryIEAbiological_process
GO:0008294Calcium- and calmodulin-responsive adenylate cyclase activityTASmolecular_function
GO:0008543Fibroblast growth factor receptor signaling pathwayTASbiological_process
GO:0016020MembraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0034199Activation of protein kinase A activityTASbiological_process
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0071377Cellular response to glucagon stimulusTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.66602771550.91051940660.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0326474492
GSE13712_SHEARDown-0.1479375210
GSE13712_STATICDown-0.0337811345
GSE19018Down-0.0348134407
GSE19899_A1Up0.0590597737
GSE19899_A2Up0.1105542906
PubMed_21979375_A1Up0.1133103812
PubMed_21979375_A2Down-0.0704387042
GSE35957Down-0.1056972766
GSE36640Up0.0532011953
GSE54402Up0.2272258185
GSE9593Down-0.0241112032
GSE43922Up0.0146001632
GSE24585Up0.2569715802
GSE37065Up0.0484597164
GSE28863_A1Up0.0029418936
GSE28863_A2Up0.0115902174
GSE28863_A3Up0.1629673891
GSE28863_A4Up0.0799659833
GSE48662Up0.0478834271

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.