HCSGD entry for ADCY7

1. General information

Official gene symbolADCY7
Entrez ID113
Gene full nameadenylate cyclase 7
Other gene symbolsAC7
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004016Adenylate cyclase activityIDA IEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005886Plasma membraneISS TAScellular_component
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0006833Water transportTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0007189Adenylate cyclase-activating G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007193Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007202Activation of phospholipase C activityTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008543Fibroblast growth factor receptor signaling pathwayTASbiological_process
GO:0009190Cyclic nucleotide biosynthetic processIEAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneIDA IEAcellular_component
GO:0016849Phosphorus-oxygen lyase activityIEAmolecular_function
GO:0030819Positive regulation of cAMP biosynthetic processIDA IEAbiological_process
GO:0034199Activation of protein kinase A activityTASbiological_process
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0060135Maternal process involved in female pregnancyIEAbiological_process
GO:0071361Cellular response to ethanolIDAbiological_process
GO:0071377Cellular response to glucagon stimulusTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.27271599480.13357288860.97015241250.7037173739

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.6618341398
GSE13712_SHEARDown-0.1695754515
GSE13712_STATICUp0.5351788195
GSE19018Down-0.4059846864
GSE19899_A1Down-0.1795900928
GSE19899_A2Up0.2152423264
PubMed_21979375_A1Down-0.1005555385
PubMed_21979375_A2Up0.4501241736
GSE35957Down-0.1651788529
GSE36640Up0.2035594722
GSE54402Up0.0019730111
GSE9593Down-0.0665166412
GSE43922Up0.3076805353
GSE24585Down-0.1546904335
GSE37065Down-0.5233007305
GSE28863_A1Up0.8919153671
GSE28863_A2Up0.5303565259
GSE28863_A3Down-0.4987614110
GSE28863_A4Down-0.0197475373
GSE48662Down-0.3686320472

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018909MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.