HCSGD entry for ADCY7

1. General information

Official gene symbolADCY7
Entrez ID113
Gene full nameadenylate cyclase 7
Other gene symbolsAC7
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004016Adenylate cyclase activityIDA IEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005886Plasma membraneISS TAScellular_component
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0006833Water transportTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0007189Adenylate cyclase-activating G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007193Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007202Activation of phospholipase C activityTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008543Fibroblast growth factor receptor signaling pathwayTASbiological_process
GO:0009190Cyclic nucleotide biosynthetic processIEAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneIDA IEAcellular_component
GO:0016849Phosphorus-oxygen lyase activityIEAmolecular_function
GO:0030819Positive regulation of cAMP biosynthetic processIDA IEAbiological_process
GO:0034199Activation of protein kinase A activityTASbiological_process
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0060135Maternal process involved in female pregnancyIEAbiological_process
GO:0071361Cellular response to ethanolIDAbiological_process
GO:0071377Cellular response to glucagon stimulusTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.27271599480.13357288860.97015241250.7037173739

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.6618341398
GSE13712_SHEARDown-0.1695754515
GSE13712_STATICUp0.5351788195
GSE19018Down-0.4059846864
GSE19899_A1Down-0.1795900928
GSE19899_A2Up0.2152423264
PubMed_21979375_A1Down-0.1005555385
PubMed_21979375_A2Up0.4501241736
GSE35957Down-0.1651788529
GSE36640Up0.2035594722
GSE54402Up0.0019730111
GSE9593Down-0.0665166412
GSE43922Up0.3076805353
GSE24585Down-0.1546904335
GSE37065Down-0.5233007305
GSE28863_A1Up0.8919153671
GSE28863_A2Up0.5303565259
GSE28863_A3Down-0.4987614110
GSE28863_A4Down-0.0197475373
GSE48662Down-0.3686320472

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018909MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.