HCSGD entry for DCTN3


1. General information

Official gene symbolDCTN3
Entrez ID11258
Gene full namedynactin 3 (p22)
Other gene symbolsDCTN-22 DCTN22
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000086G2/M transition of mitotic cell cycleTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000777Condensed chromosome kinetochoreIEAcellular_component
GO:0000910CytokinesisIDAbiological_process
GO:0005198Structural molecule activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005813CentrosomeIDAcellular_component
GO:0005819SpindleIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005869Dynactin complexIPIcellular_component
GO:0007017Microtubule-based processIEAbiological_process
GO:0007067MitosisIEAbiological_process
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IITASbiological_process
GO:0030496MidbodyIEAcellular_component
GO:0032154Cleavage furrowIEAcellular_component
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.74939409980.22571037190.99999024730.9139881077

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3453003512
GSE13712_SHEARDown-0.5032204553
GSE13712_STATICDown-0.2674230948
GSE19018Up0.4527342710
GSE19899_A1Down-0.4415008950
GSE19899_A2Up0.2087007941
PubMed_21979375_A1Down-0.5618851943
PubMed_21979375_A2Down-0.0321705751
GSE35957Down-0.2245407174
GSE36640Up0.1214487001
GSE54402Down-0.1887487449
GSE9593Up0.2787979899
GSE43922Down-0.1805816024
GSE24585Up0.2775395564
GSE37065Down-0.2266889036
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.1471045456

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022659Proteomics;MicroarrayFunctional MTI (Weak)18668037
hsa-miR-26b-5pMIMAT0000083MIRT029403MicroarrayFunctional MTI (Weak)19088304
hsa-miR-877-3pMIMAT0004950MIRT037021CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT041712CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.