HCSGD entry for DCTN3
1. General information
| Official gene symbol | DCTN3 |
|---|---|
| Entrez ID | 11258 |
| Gene full name | dynactin 3 (p22) |
| Other gene symbols | DCTN-22 DCTN22 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000777 | Condensed chromosome kinetochore | IEA | cellular_component |
| GO:0000910 | Cytokinesis | IDA | biological_process |
| GO:0005198 | Structural molecule activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005819 | Spindle | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005869 | Dynactin complex | IPI | cellular_component |
| GO:0007017 | Microtubule-based process | IEA | biological_process |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
| GO:0030496 | Midbody | IEA | cellular_component |
| GO:0032154 | Cleavage furrow | IEA | cellular_component |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7493940998 | 0.2257103719 | 0.9999902473 | 0.9139881077 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3453003512 |
| GSE13712_SHEAR | Down | -0.5032204553 |
| GSE13712_STATIC | Down | -0.2674230948 |
| GSE19018 | Up | 0.4527342710 |
| GSE19899_A1 | Down | -0.4415008950 |
| GSE19899_A2 | Up | 0.2087007941 |
| PubMed_21979375_A1 | Down | -0.5618851943 |
| PubMed_21979375_A2 | Down | -0.0321705751 |
| GSE35957 | Down | -0.2245407174 |
| GSE36640 | Up | 0.1214487001 |
| GSE54402 | Down | -0.1887487449 |
| GSE9593 | Up | 0.2787979899 |
| GSE43922 | Down | -0.1805816024 |
| GSE24585 | Up | 0.2775395564 |
| GSE37065 | Down | -0.2266889036 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.1471045456 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022659 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029403 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037021 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041712 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
