HCSGD entry for ZWINT


1. General information

Official gene symbolZWINT
Entrez ID11130
Gene full nameZW10 interacting kinetochore protein
Other gene symbolsHZwint-1 KNTC2AP ZWINT1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000070Mitotic sister chromatid segregationIDAbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000776KinetochoreIDAcellular_component
GO:0000777Condensed chromosome kinetochoreIEAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIDA IEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0007049Cell cycleNASbiological_process
GO:0007051Spindle organizationNASbiological_process
GO:0007093Mitotic cell cycle checkpointIDAbiological_process
GO:0030425DendriteIEAcellular_component
GO:0047485Protein N-terminus bindingIPImolecular_function
GO:0048015Phosphatidylinositol-mediated signalingNASbiological_process
GO:0051649Establishment of localization in cellIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.96792964170.00003288630.99999024730.0101835294

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-1.1476345603
GSE13712_SHEARDown-0.8569978011
GSE13712_STATICDown-0.4192378726
GSE19018Down-0.7887900692
GSE19899_A1Down-2.0871072209
GSE19899_A2Down-2.2194309164
PubMed_21979375_A1Down-2.2753676868
PubMed_21979375_A2Down-2.6672564892
GSE35957Down-3.2946984764
GSE36640Down-2.2351841934
GSE54402Down-0.4231874381
GSE9593Down-1.3317996899
GSE43922Down-0.9890036418
GSE24585Up0.0271964807
GSE37065Down-0.2176641519
GSE28863_A1Down-0.3824012518
GSE28863_A2Up0.9231148296
GSE28863_A3Down-0.5699455845
GSE28863_A4Up0.4403224622
GSE48662Down-1.6967624997

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193b-3pMIMAT0002819MIRT016569MicroarrayFunctional MTI (Weak)20304954
hsa-miR-124-3pMIMAT0000422MIRT022987MicroarrayFunctional MTI (Weak)18668037
hsa-miR-26b-5pMIMAT0000083MIRT029953MicroarrayFunctional MTI (Weak)19088304
hsa-miR-92a-1-5pMIMAT0004507MIRT038916CLASHFunctional MTI (Weak)23622248
hsa-miR-149-5pMIMAT0000450MIRT045620CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049834CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.