HCSGD entry for ZWINT
1. General information
| Official gene symbol | ZWINT |
|---|---|
| Entrez ID | 11130 |
| Gene full name | ZW10 interacting kinetochore protein |
| Other gene symbols | HZwint-1 KNTC2AP ZWINT1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000070 | Mitotic sister chromatid segregation | IDA | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000776 | Kinetochore | IDA | cellular_component |
| GO:0000777 | Condensed chromosome kinetochore | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007049 | Cell cycle | NAS | biological_process |
| GO:0007051 | Spindle organization | NAS | biological_process |
| GO:0007093 | Mitotic cell cycle checkpoint | IDA | biological_process |
| GO:0030425 | Dendrite | IEA | cellular_component |
| GO:0047485 | Protein N-terminus binding | IPI | molecular_function |
| GO:0048015 | Phosphatidylinositol-mediated signaling | NAS | biological_process |
| GO:0051649 | Establishment of localization in cell | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9679296417 | 0.0000328863 | 0.9999902473 | 0.0101835294 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.1476345603 |
| GSE13712_SHEAR | Down | -0.8569978011 |
| GSE13712_STATIC | Down | -0.4192378726 |
| GSE19018 | Down | -0.7887900692 |
| GSE19899_A1 | Down | -2.0871072209 |
| GSE19899_A2 | Down | -2.2194309164 |
| PubMed_21979375_A1 | Down | -2.2753676868 |
| PubMed_21979375_A2 | Down | -2.6672564892 |
| GSE35957 | Down | -3.2946984764 |
| GSE36640 | Down | -2.2351841934 |
| GSE54402 | Down | -0.4231874381 |
| GSE9593 | Down | -1.3317996899 |
| GSE43922 | Down | -0.9890036418 |
| GSE24585 | Up | 0.0271964807 |
| GSE37065 | Down | -0.2176641519 |
| GSE28863_A1 | Down | -0.3824012518 |
| GSE28863_A2 | Up | 0.9231148296 |
| GSE28863_A3 | Down | -0.5699455845 |
| GSE28863_A4 | Up | 0.4403224622 |
| GSE48662 | Down | -1.6967624997 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016569 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022987 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029953 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-92a-1-5p | MIMAT0004507 | MIRT038916 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045620 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049834 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
