HCSGD entry for FGFR1OP

1. General information

Official gene symbolFGFR1OP
Entrez ID11116
Gene full nameFGFR1 oncogene partner
Other gene symbolsFOP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000086G2/M transition of mitotic cell cycleTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0004713Protein tyrosine kinase activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005813CentrosomeIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006468Protein phosphorylationTASbiological_process
GO:0006469Negative regulation of protein kinase activityIDAbiological_process
GO:0008152Metabolic processTASbiological_process
GO:0008284Positive regulation of cell proliferationIDAbiological_process
GO:0016310PhosphorylationTASbiological_process
GO:0018108Peptidyl-tyrosine phosphorylationTASbiological_process
GO:0019901Protein kinase bindingIPImolecular_function
GO:0030292Protein tyrosine kinase inhibitor activityIDAmolecular_function
GO:0030307Positive regulation of cell growthIDAbiological_process
GO:0030335Positive regulation of cell migrationIDAbiological_process
GO:0034453Microtubule anchoringIEAbiological_process
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
GO:0061099Negative regulation of protein tyrosine kinase activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.25939163410.63516648680.95288865321.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1027936052
GSE13712_SHEARUp0.0026626509
GSE13712_STATICDown-0.1302207186
GSE19018Up0.1092728495
GSE19899_A1Up0.2262986567
GSE19899_A2Up0.1914620023
PubMed_21979375_A1Up0.6512296569
PubMed_21979375_A2Up0.0513224157
GSE35957Down-0.1971579634
GSE36640Down-0.8626205093
GSE54402Up0.5728258279
GSE9593Down-0.2524047739
GSE43922Up0.2989194856
GSE24585Down-0.1394422361
GSE37065Up0.0935598164
GSE28863_A1Up0.0930934154
GSE28863_A2Up0.0619227139
GSE28863_A3Down-0.1905393821
GSE28863_A4Up0.0289632885
GSE48662Down-0.2657821030

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-192-5pMIMAT0000222MIRT026178MicroarrayFunctional MTI (Weak)19074876
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.