HCSGD entry for FGFR1OP
1. General information
| Official gene symbol | FGFR1OP |
|---|---|
| Entrez ID | 11116 |
| Gene full name | FGFR1 oncogene partner |
| Other gene symbols | FOP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0004713 | Protein tyrosine kinase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006468 | Protein phosphorylation | TAS | biological_process |
| GO:0006469 | Negative regulation of protein kinase activity | IDA | biological_process |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | IDA | biological_process |
| GO:0016310 | Phosphorylation | TAS | biological_process |
| GO:0018108 | Peptidyl-tyrosine phosphorylation | TAS | biological_process |
| GO:0019901 | Protein kinase binding | IPI | molecular_function |
| GO:0030292 | Protein tyrosine kinase inhibitor activity | IDA | molecular_function |
| GO:0030307 | Positive regulation of cell growth | IDA | biological_process |
| GO:0030335 | Positive regulation of cell migration | IDA | biological_process |
| GO:0034453 | Microtubule anchoring | IEA | biological_process |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
| GO:0061099 | Negative regulation of protein tyrosine kinase activity | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2593916341 | 0.6351664868 | 0.9528886532 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1027936052 |
| GSE13712_SHEAR | Up | 0.0026626509 |
| GSE13712_STATIC | Down | -0.1302207186 |
| GSE19018 | Up | 0.1092728495 |
| GSE19899_A1 | Up | 0.2262986567 |
| GSE19899_A2 | Up | 0.1914620023 |
| PubMed_21979375_A1 | Up | 0.6512296569 |
| PubMed_21979375_A2 | Up | 0.0513224157 |
| GSE35957 | Down | -0.1971579634 |
| GSE36640 | Down | -0.8626205093 |
| GSE54402 | Up | 0.5728258279 |
| GSE9593 | Down | -0.2524047739 |
| GSE43922 | Up | 0.2989194856 |
| GSE24585 | Down | -0.1394422361 |
| GSE37065 | Up | 0.0935598164 |
| GSE28863_A1 | Up | 0.0930934154 |
| GSE28863_A2 | Up | 0.0619227139 |
| GSE28863_A3 | Down | -0.1905393821 |
| GSE28863_A4 | Up | 0.0289632885 |
| GSE48662 | Down | -0.2657821030 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT026178 | Microarray | Functional MTI (Weak) | 19074876 |
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