HCSGD entry for LILRB4


1. General information

Official gene symbolLILRB4
Entrez ID11006
Gene full nameleukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
Other gene symbolsCD85K ILT-3 ILT3 LIR-5 LIR5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002376Immune system processIEAbiological_process
GO:0003823Antigen bindingTASmolecular_function
GO:0004872Receptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneIEAcellular_component
GO:0007165Signal transductionTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0045671Negative regulation of osteoclast differentiationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82846866760.68352702400.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0812810358
GSE13712_SHEARUp0.1137627718
GSE13712_STATICDown-0.0464181139
GSE19018Up0.0736186903
GSE19899_A1Up0.1761807144
GSE19899_A2Down-0.1319563106
PubMed_21979375_A1Down-0.0153971420
PubMed_21979375_A2Down-0.1504392503
GSE35957Up0.0411957891
GSE36640Up0.0899437239
GSE54402Up0.0123083523
GSE9593Down-0.0810250112
GSE43922Up0.0231708843
GSE24585Up0.0534000258
GSE37065Up0.0338117984
GSE28863_A1Down-0.1502799382
GSE28863_A2Down-0.1776037126
GSE28863_A3Up0.2242307135
GSE28863_A4Down-0.0041742940
GSE48662Up0.0327129183

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017863MicroarrayFunctional MTI (Weak)18185580
hsa-let-7a-5pMIMAT0000062MIRT052507CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.