HCSGD entry for LILRB4
1. General information
| Official gene symbol | LILRB4 |
|---|---|
| Entrez ID | 11006 |
| Gene full name | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 |
| Other gene symbols | CD85K ILT-3 ILT3 LIR-5 LIR5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002376 | Immune system process | IEA | biological_process |
| GO:0003823 | Antigen binding | TAS | molecular_function |
| GO:0004872 | Receptor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0045671 | Negative regulation of osteoclast differentiation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8284686676 | 0.6835270240 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0812810358 |
| GSE13712_SHEAR | Up | 0.1137627718 |
| GSE13712_STATIC | Down | -0.0464181139 |
| GSE19018 | Up | 0.0736186903 |
| GSE19899_A1 | Up | 0.1761807144 |
| GSE19899_A2 | Down | -0.1319563106 |
| PubMed_21979375_A1 | Down | -0.0153971420 |
| PubMed_21979375_A2 | Down | -0.1504392503 |
| GSE35957 | Up | 0.0411957891 |
| GSE36640 | Up | 0.0899437239 |
| GSE54402 | Up | 0.0123083523 |
| GSE9593 | Down | -0.0810250112 |
| GSE43922 | Up | 0.0231708843 |
| GSE24585 | Up | 0.0534000258 |
| GSE37065 | Up | 0.0338117984 |
| GSE28863_A1 | Down | -0.1502799382 |
| GSE28863_A2 | Down | -0.1776037126 |
| GSE28863_A3 | Up | 0.2242307135 |
| GSE28863_A4 | Down | -0.0041742940 |
| GSE48662 | Up | 0.0327129183 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017863 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052507 | CLASH | Functional MTI (Weak) | 23622248 |
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