HCSGD entry for SDS

1. General information

Official gene symbolSDS
Entrez ID10993
Gene full nameserine dehydratase
Other gene symbolsSDH
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003941L-serine ammonia-lyase activityIDAmolecular_function
GO:0004794L-threonine ammonia-lyase activityIEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0006094GluconeogenesisIEAbiological_process
GO:0006520Cellular amino acid metabolic processIEAbiological_process
GO:0006565L-serine catabolic processIDAbiological_process
GO:0030170Pyridoxal phosphate bindingIDA IEAmolecular_function
GO:0033590Response to cobalaminIEAbiological_process
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0042866Pyruvate biosynthetic processIDAbiological_process
GO:0043200Response to amino acidIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.73310197560.74431732080.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0296322204
GSE13712_SHEARUp0.0354668678
GSE13712_STATICUp0.0135161530
GSE19018Down-0.0547591195
GSE19899_A1Up0.0412956698
GSE19899_A2Up0.1165918649
PubMed_21979375_A1Down-0.0378121102
PubMed_21979375_A2Down-0.2084254373
GSE35957Up0.0865906437
GSE36640Down-0.1150508924
GSE54402Up0.0772071181
GSE9593Down-0.1192922764
GSE43922Up0.0250081846
GSE24585Up0.2510766699
GSE37065Down-0.2188597138
GSE28863_A1Down-0.0083203595
GSE28863_A2Up0.0094411417
GSE28863_A3Up0.1345111365
GSE28863_A4Up0.2061125414
GSE48662Up0.0917334004

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 3 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

18056958Moreover, the patterns of modified proteins obtained after separation by SDS gel electrophoresis were indicative of preferential protein targets for both modifications
9191026Expression of the transgenes, all of which retained the C-terminal catalytic domain, was monitored by immunofluorescence staining, Northern blot analysis and SDS gel electrophoresis
38895155-15% gradient SDS gels
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