HCSGD entry for SDS
1. General information
| Official gene symbol | SDS |
|---|---|
| Entrez ID | 10993 |
| Gene full name | serine dehydratase |
| Other gene symbols | SDH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003941 | L-serine ammonia-lyase activity | IDA | molecular_function |
| GO:0004794 | L-threonine ammonia-lyase activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0006094 | Gluconeogenesis | IEA | biological_process |
| GO:0006520 | Cellular amino acid metabolic process | IEA | biological_process |
| GO:0006565 | L-serine catabolic process | IDA | biological_process |
| GO:0030170 | Pyridoxal phosphate binding | IDA IEA | molecular_function |
| GO:0033590 | Response to cobalamin | IEA | biological_process |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
| GO:0042866 | Pyruvate biosynthetic process | IDA | biological_process |
| GO:0043200 | Response to amino acid | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7331019756 | 0.7443173208 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0296322204 |
| GSE13712_SHEAR | Up | 0.0354668678 |
| GSE13712_STATIC | Up | 0.0135161530 |
| GSE19018 | Down | -0.0547591195 |
| GSE19899_A1 | Up | 0.0412956698 |
| GSE19899_A2 | Up | 0.1165918649 |
| PubMed_21979375_A1 | Down | -0.0378121102 |
| PubMed_21979375_A2 | Down | -0.2084254373 |
| GSE35957 | Up | 0.0865906437 |
| GSE36640 | Down | -0.1150508924 |
| GSE54402 | Up | 0.0772071181 |
| GSE9593 | Down | -0.1192922764 |
| GSE43922 | Up | 0.0250081846 |
| GSE24585 | Up | 0.2510766699 |
| GSE37065 | Down | -0.2188597138 |
| GSE28863_A1 | Down | -0.0083203595 |
| GSE28863_A2 | Up | 0.0094411417 |
| GSE28863_A3 | Up | 0.1345111365 |
| GSE28863_A4 | Up | 0.2061125414 |
| GSE48662 | Up | 0.0917334004 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 3 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 18056958 | Moreover, the patterns of modified proteins obtained after separation by SDS gel electrophoresis were indicative of preferential protein targets for both modifications |
| 9191026 | Expression of the transgenes, all of which retained the C-terminal catalytic domain, was monitored by immunofluorescence staining, Northern blot analysis and SDS gel electrophoresis |
| 3889515 | 5-15% gradient SDS gels |
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