HCSGD entry for KDELR1
1. General information
| Official gene symbol | KDELR1 |
|---|---|
| Entrez ID | 10945 |
| Gene full name | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 |
| Other gene symbols | ERD2 ERD2.1 HDEL PM23 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005046 | KDEL sequence binding | TAS | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0005793 | Endoplasmic reticulum-Golgi intermediate compartment | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005801 | Cis-Golgi network | IEA | cellular_component |
| GO:0006621 | Protein retention in ER lumen | IEA | biological_process |
| GO:0006886 | Intracellular protein transport | TAS | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016192 | Vesicle-mediated transport | IEA | biological_process |
| GO:0030663 | COPI-coated vesicle membrane | IEA | cellular_component |
| GO:0033116 | Endoplasmic reticulum-Golgi intermediate compartment membrane | IEA | cellular_component |
| GO:0046923 | ER retention sequence binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4584193306 | 0.3349911212 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2859440341 |
| GSE13712_SHEAR | Down | -0.1672461191 |
| GSE13712_STATIC | Down | -0.1564744615 |
| GSE19018 | Up | 0.1629051925 |
| GSE19899_A1 | Down | -0.2604031876 |
| GSE19899_A2 | Up | 0.4570208404 |
| PubMed_21979375_A1 | Up | 0.1078103781 |
| PubMed_21979375_A2 | Down | -0.0367006587 |
| GSE35957 | Up | 0.0429104506 |
| GSE36640 | Up | 0.3653642030 |
| GSE54402 | Down | -0.0471432303 |
| GSE9593 | Up | 0.3476427437 |
| GSE43922 | Up | 0.2298887083 |
| GSE24585 | Down | -0.2469392463 |
| GSE37065 | Down | -0.1295533684 |
| GSE28863_A1 | Down | -0.1372120373 |
| GSE28863_A2 | Down | -0.4209904051 |
| GSE28863_A3 | Down | -0.2747928200 |
| GSE28863_A4 | Up | 0.0948837869 |
| GSE48662 | Down | -0.2777198906 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023631 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-96-5p | MIMAT0000095 | MIRT027910 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037161 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-769-3p | MIMAT0003887 | MIRT039070 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040446 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042609 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044760 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049826 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052299 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
