HCSGD entry for KDELR1


1. General information

Official gene symbolKDELR1
Entrez ID10945
Gene full nameKDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
Other gene symbolsERD2 ERD2.1 HDEL PM23
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005046KDEL sequence bindingTASmolecular_function
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0005793Endoplasmic reticulum-Golgi intermediate compartmentIDAcellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0005801Cis-Golgi networkIEAcellular_component
GO:0006621Protein retention in ER lumenIEAbiological_process
GO:0006886Intracellular protein transportTASbiological_process
GO:0015031Protein transportIEAbiological_process
GO:0016020MembraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0016192Vesicle-mediated transportIEAbiological_process
GO:0030663COPI-coated vesicle membraneIEAcellular_component
GO:0033116Endoplasmic reticulum-Golgi intermediate compartment membraneIEAcellular_component
GO:0046923ER retention sequence bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.45841933060.33499112120.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2859440341
GSE13712_SHEARDown-0.1672461191
GSE13712_STATICDown-0.1564744615
GSE19018Up0.1629051925
GSE19899_A1Down-0.2604031876
GSE19899_A2Up0.4570208404
PubMed_21979375_A1Up0.1078103781
PubMed_21979375_A2Down-0.0367006587
GSE35957Up0.0429104506
GSE36640Up0.3653642030
GSE54402Down-0.0471432303
GSE9593Up0.3476427437
GSE43922Up0.2298887083
GSE24585Down-0.2469392463
GSE37065Down-0.1295533684
GSE28863_A1Down-0.1372120373
GSE28863_A2Down-0.4209904051
GSE28863_A3Down-0.2747928200
GSE28863_A4Up0.0948837869
GSE48662Down-0.2777198906

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT023631ProteomicsFunctional MTI (Weak)18668040
hsa-miR-96-5pMIMAT0000095MIRT027910SequencingFunctional MTI (Weak)20371350
hsa-miR-877-3pMIMAT0004950MIRT037161CLASHFunctional MTI (Weak)23622248
hsa-miR-769-3pMIMAT0003887MIRT039070CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT040446CLASHFunctional MTI (Weak)23622248
hsa-miR-423-3pMIMAT0001340MIRT042609CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044760CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049826CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT052299CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.