HCSGD entry for RNPS1
1. General information
| Official gene symbol | RNPS1 |
|---|---|
| Entrez ID | 10921 |
| Gene full name | RNA binding protein S1, serine-rich domain |
| Other gene symbols | E5.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000184 | Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | IDA IMP TAS | biological_process |
| GO:0000381 | Regulation of alternative mRNA splicing, via spliceosome | IMP | biological_process |
| GO:0000398 | MRNA splicing, via spliceosome | TAS | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IDA | molecular_function |
| GO:0003730 | MRNA 3'-UTR binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | TAS | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006369 | Termination of RNA polymerase II transcription | TAS | biological_process |
| GO:0006406 | MRNA export from nucleus | TAS | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0016607 | Nuclear speck | IEA | cellular_component |
| GO:0031124 | MRNA 3'-end processing | TAS | biological_process |
| GO:0035145 | Exon-exon junction complex | TAS | cellular_component |
| GO:0043065 | Positive regulation of apoptotic process | IDA | biological_process |
| GO:0048025 | Negative regulation of mRNA splicing, via spliceosome | IDA | biological_process |
| GO:0061574 | ASAP complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8976501311 | 0.2068034269 | 0.9999902473 | 0.8813953206 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0092256087 |
| GSE13712_SHEAR | Up | 0.1046343599 |
| GSE13712_STATIC | Down | -0.0048644625 |
| GSE19018 | Down | -0.2161449105 |
| GSE19899_A1 | Down | -0.2787715112 |
| GSE19899_A2 | Up | 0.2080730099 |
| PubMed_21979375_A1 | Up | 0.4852129649 |
| PubMed_21979375_A2 | Up | 0.1593100153 |
| GSE35957 | Down | -0.2337997346 |
| GSE36640 | Down | -0.5908591333 |
| GSE54402 | Up | 0.1691409990 |
| GSE9593 | Down | -0.4614290991 |
| GSE43922 | Up | 0.0274695600 |
| GSE24585 | Down | -0.1360165751 |
| GSE37065 | Down | -0.1902534438 |
| GSE28863_A1 | Down | -0.1523580981 |
| GSE28863_A2 | Up | 0.0321909426 |
| GSE28863_A3 | Down | -0.0635026380 |
| GSE28863_A4 | Up | 0.0510147983 |
| GSE48662 | Down | -0.3464726206 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1296-5p | MIMAT0005794 | MIRT036145 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-342-5p | MIMAT0004694 | MIRT038223 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30b-3p | MIMAT0004589 | MIRT038651 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040364 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043958 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044270 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045589 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047858 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049704 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
