HCSGD entry for RNPS1

1. General information

Official gene symbolRNPS1
Entrez ID10921
Gene full nameRNA binding protein S1, serine-rich domain
Other gene symbolsE5.1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0000184Nuclear-transcribed mRNA catabolic process, nonsense-mediated decayIDA IMP TASbiological_process
GO:0000381Regulation of alternative mRNA splicing, via spliceosomeIMPbiological_process
GO:0000398MRNA splicing, via spliceosomeTASbiological_process
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003723RNA bindingIDAmolecular_function
GO:0003730MRNA 3'-UTR bindingIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006351Transcription, DNA-templatedTASbiological_process
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006369Termination of RNA polymerase II transcriptionTASbiological_process
GO:0006406MRNA export from nucleusTASbiological_process
GO:0008380RNA splicingTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0016607Nuclear speckIEAcellular_component
GO:0031124MRNA 3'-end processingTASbiological_process
GO:0035145Exon-exon junction complexTAScellular_component
GO:0043065Positive regulation of apoptotic processIDAbiological_process
GO:0048025Negative regulation of mRNA splicing, via spliceosomeIDAbiological_process
GO:0061574ASAP complexIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.89765013110.20680342690.99999024730.8813953206

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0092256087
GSE13712_SHEARUp0.1046343599
GSE13712_STATICDown-0.0048644625
GSE19018Down-0.2161449105
GSE19899_A1Down-0.2787715112
GSE19899_A2Up0.2080730099
PubMed_21979375_A1Up0.4852129649
PubMed_21979375_A2Up0.1593100153
GSE35957Down-0.2337997346
GSE36640Down-0.5908591333
GSE54402Up0.1691409990
GSE9593Down-0.4614290991
GSE43922Up0.0274695600
GSE24585Down-0.1360165751
GSE37065Down-0.1902534438
GSE28863_A1Down-0.1523580981
GSE28863_A2Up0.0321909426
GSE28863_A3Down-0.0635026380
GSE28863_A4Up0.0510147983
GSE48662Down-0.3464726206

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1296-5pMIMAT0005794MIRT036145CLASHFunctional MTI (Weak)23622248
hsa-miR-342-5pMIMAT0004694MIRT038223CLASHFunctional MTI (Weak)23622248
hsa-miR-30b-3pMIMAT0004589MIRT038651CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT040364CLASHFunctional MTI (Weak)23622248
hsa-miR-378a-3pMIMAT0000732MIRT043958CLASHFunctional MTI (Weak)23622248
hsa-miR-106b-5pMIMAT0000680MIRT044270CLASHFunctional MTI (Weak)23622248
hsa-miR-149-5pMIMAT0000450MIRT045589CLASHFunctional MTI (Weak)23622248
hsa-miR-30c-5pMIMAT0000244MIRT047858CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049704CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.