HCSGD entry for BRD8
1. General information
| Official gene symbol | BRD8 |
|---|---|
| Entrez ID | 10902 |
| Gene full name | bromodomain containing 8 |
| Other gene symbols | SMAP SMAP2 p120 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | NAS | molecular_function |
| GO:0004887 | Thyroid hormone receptor activity | TAS | molecular_function |
| GO:0005634 | Nucleus | IDA NAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | NAS | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007166 | Cell surface receptor signaling pathway | TAS | biological_process |
| GO:0030522 | Intracellular receptor signaling pathway | TAS | biological_process |
| GO:0035267 | NuA4 histone acetyltransferase complex | IDA | cellular_component |
| GO:0040008 | Regulation of growth | IEA | biological_process |
| GO:0043967 | Histone H4 acetylation | IDA | biological_process |
| GO:0043968 | Histone H2A acetylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6739788382 | 0.3986933703 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2083522127 |
| GSE13712_SHEAR | Down | -0.0554141003 |
| GSE13712_STATIC | Down | -0.1185050075 |
| GSE19018 | Down | -0.0502300057 |
| GSE19899_A1 | Up | 0.0369152343 |
| GSE19899_A2 | Down | -0.3615608539 |
| PubMed_21979375_A1 | Down | -0.1600870938 |
| PubMed_21979375_A2 | Down | -0.3028173912 |
| GSE35957 | Down | -0.4539675103 |
| GSE36640 | Down | -0.3806662451 |
| GSE54402 | Down | -0.0775061740 |
| GSE9593 | Down | -0.1810854707 |
| GSE43922 | Up | 0.0183372301 |
| GSE24585 | Up | 0.5588839243 |
| GSE37065 | Up | 0.0022405852 |
| GSE28863_A1 | Up | 0.0844790177 |
| GSE28863_A2 | Up | 0.3839559942 |
| GSE28863_A3 | Up | 0.4148394747 |
| GSE28863_A4 | Down | -0.0585348441 |
| GSE48662 | Down | -0.1123390427 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030145 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030616 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040691 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
