HCSGD entry for BRD8


1. General information

Official gene symbolBRD8
Entrez ID10902
Gene full namebromodomain containing 8
Other gene symbolsSMAP SMAP2 p120
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003700Sequence-specific DNA binding transcription factor activityNASmolecular_function
GO:0004887Thyroid hormone receptor activityTASmolecular_function
GO:0005634NucleusIDA NAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0006355Regulation of transcription, DNA-templatedNASbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007166Cell surface receptor signaling pathwayTASbiological_process
GO:0030522Intracellular receptor signaling pathwayTASbiological_process
GO:0035267NuA4 histone acetyltransferase complexIDAcellular_component
GO:0040008Regulation of growthIEAbiological_process
GO:0043967Histone H4 acetylationIDAbiological_process
GO:0043968Histone H2A acetylationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.67397883820.39869337030.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2083522127
GSE13712_SHEARDown-0.0554141003
GSE13712_STATICDown-0.1185050075
GSE19018Down-0.0502300057
GSE19899_A1Up0.0369152343
GSE19899_A2Down-0.3615608539
PubMed_21979375_A1Down-0.1600870938
PubMed_21979375_A2Down-0.3028173912
GSE35957Down-0.4539675103
GSE36640Down-0.3806662451
GSE54402Down-0.0775061740
GSE9593Down-0.1810854707
GSE43922Up0.0183372301
GSE24585Up0.5588839243
GSE37065Up0.0022405852
GSE28863_A1Up0.0844790177
GSE28863_A2Up0.3839559942
GSE28863_A3Up0.4148394747
GSE28863_A4Down-0.0585348441
GSE48662Down-0.1123390427

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT030145MicroarrayFunctional MTI (Weak)19088304
hsa-miR-24-3pMIMAT0000080MIRT030616SequencingFunctional MTI (Weak)20371350
hsa-miR-92b-3pMIMAT0003218MIRT040691CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.