HCSGD entry for ADCY3

1. General information

Official gene symbolADCY3
Entrez ID109
Gene full nameadenylate cyclase 3
Other gene symbolsAC3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0004016Adenylate cyclase activityIEAmolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0005929CiliumIEAcellular_component
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0006833Water transportTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0007189Adenylate cyclase-activating G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007193Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007202Activation of phospholipase C activityTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007608Sensory perception of smellIEAbiological_process
GO:0008543Fibroblast growth factor receptor signaling pathwayTASbiological_process
GO:0009190Cyclic nucleotide biosynthetic processIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016849Phosphorus-oxygen lyase activityIEAmolecular_function
GO:0034199Activation of protein kinase A activityTASbiological_process
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0071377Cellular response to glucagon stimulusTASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97965703430.00094600890.99999024730.0579451163

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3750359290
GSE13712_SHEARUp0.1045770781
GSE13712_STATICUp0.0993288613
GSE19018Down-0.4822239454
GSE19899_A1Down-0.3733175290
GSE19899_A2Down-1.7140867601
PubMed_21979375_A1Down-1.1039759363
PubMed_21979375_A2Down-1.0736401184
GSE35957Down-0.1442040510
GSE36640Down-2.1350103082
GSE54402Down-0.4574640241
GSE9593Down-0.5294865599
GSE43922Down-0.9033129234
GSE24585Down-1.2762361186
GSE37065Down-0.2575077010
GSE28863_A1Up0.3521321704
GSE28863_A2Up0.4250229723
GSE28863_A3Down-0.2798611804
GSE28863_A4Down-0.2167148402
GSE48662Down-0.1950249237

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022973MicroarrayFunctional MTI (Weak)18668037
hsa-miR-1301-3pMIMAT0005797MIRT035974CLASHFunctional MTI (Weak)23622248
hsa-miR-1296-5pMIMAT0005794MIRT036106CLASHFunctional MTI (Weak)23622248
hsa-miR-877-5pMIMAT0004949MIRT037340CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.