HCSGD entry for RAB10

1. General information

Official gene symbolRAB10
Entrez ID10890
Gene full nameRAB10, member RAS oncogene family
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000145ExocystISScellular_component
GO:0003924GTPase activityEXPmolecular_function
GO:0005525GTP bindingIDAmolecular_function
GO:0005768EndosomeIDAcellular_component
GO:0005789Endoplasmic reticulum membraneIDAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0005802Trans-Golgi networkISScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006184GTP catabolic processEXPbiological_process
GO:0006893Golgi to plasma membrane transportISSbiological_process
GO:0007264Small GTPase mediated signal transductionIEAbiological_process
GO:0007409AxonogenesisISSbiological_process
GO:0008152Metabolic processEXPbiological_process
GO:0016192Vesicle-mediated transportISSbiological_process
GO:0016197Endosomal transportIMPbiological_process
GO:0019003GDP bindingIDAmolecular_function
GO:0030659Cytoplasmic vesicle membraneTAScellular_component
GO:0030670Phagocytic vesicle membraneIEAcellular_component
GO:0030859Polarized epithelial cell differentiationISSbiological_process
GO:0031489Myosin V bindingIPImolecular_function
GO:0032593Insulin-responsive compartmentIDAcellular_component
GO:0032869Cellular response to insulin stimulusISSbiological_process
GO:0043001Golgi to plasma membrane protein transportISSbiological_process
GO:0045200Establishment of neuroblast polarityISSbiological_process
GO:0055037Recycling endosomeIDAcellular_component
GO:0055038Recycling endosome membraneIEAcellular_component
GO:0061467Basolateral protein localizationISSbiological_process
GO:0071782Endoplasmic reticulum tubular networkIDAcellular_component
GO:0071786Endoplasmic reticulum tubular network organizationIMPbiological_process
GO:0072372Primary ciliumIDAcellular_component
GO:0072659Protein localization to plasma membraneISSbiological_process
GO:0097051Establishment of protein localization to endoplasmic reticulum membraneIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.40831583150.66816430610.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2685758029
GSE13712_SHEARDown-0.0097419828
GSE13712_STATICUp0.0832124348
GSE19018Up0.2195856447
GSE19899_A1Down-0.0688067794
GSE19899_A2Up0.1161506198
PubMed_21979375_A1Up0.0603933391
PubMed_21979375_A2Down-0.0365781783
GSE35957Up0.1205487071
GSE36640Up0.1226344948
GSE54402Up0.1004255566
GSE9593Up0.6725344606
GSE43922Down-0.0135747356
GSE24585Down-0.3327409473
GSE37065Up0.1192433313
GSE28863_A1Down-0.0691899246
GSE28863_A2Up0.3365986921
GSE28863_A3Down-0.2206724961
GSE28863_A4Down-0.3418429334
GSE48662Down-0.2235569548

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-375MIMAT0000728MIRT019696qRT-PCR;MicroarrayFunctional MTI (Weak)20584986
hsa-miR-148a-3pMIMAT0000243MIRT025986SequencingFunctional MTI (Weak)20371350
hsa-miR-877-3pMIMAT0004950MIRT037193CLASHFunctional MTI (Weak)23622248
hsa-let-7c-5pMIMAT0000064MIRT051750CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT052065CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.