HCSGD entry for RAB10
1. General information
| Official gene symbol | RAB10 |
|---|---|
| Entrez ID | 10890 |
| Gene full name | RAB10, member RAS oncogene family |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000145 | Exocyst | ISS | cellular_component |
| GO:0003924 | GTPase activity | EXP | molecular_function |
| GO:0005525 | GTP binding | IDA | molecular_function |
| GO:0005768 | Endosome | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005802 | Trans-Golgi network | ISS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006184 | GTP catabolic process | EXP | biological_process |
| GO:0006893 | Golgi to plasma membrane transport | ISS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0007409 | Axonogenesis | ISS | biological_process |
| GO:0008152 | Metabolic process | EXP | biological_process |
| GO:0016192 | Vesicle-mediated transport | ISS | biological_process |
| GO:0016197 | Endosomal transport | IMP | biological_process |
| GO:0019003 | GDP binding | IDA | molecular_function |
| GO:0030659 | Cytoplasmic vesicle membrane | TAS | cellular_component |
| GO:0030670 | Phagocytic vesicle membrane | IEA | cellular_component |
| GO:0030859 | Polarized epithelial cell differentiation | ISS | biological_process |
| GO:0031489 | Myosin V binding | IPI | molecular_function |
| GO:0032593 | Insulin-responsive compartment | IDA | cellular_component |
| GO:0032869 | Cellular response to insulin stimulus | ISS | biological_process |
| GO:0043001 | Golgi to plasma membrane protein transport | ISS | biological_process |
| GO:0045200 | Establishment of neuroblast polarity | ISS | biological_process |
| GO:0055037 | Recycling endosome | IDA | cellular_component |
| GO:0055038 | Recycling endosome membrane | IEA | cellular_component |
| GO:0061467 | Basolateral protein localization | ISS | biological_process |
| GO:0071782 | Endoplasmic reticulum tubular network | IDA | cellular_component |
| GO:0071786 | Endoplasmic reticulum tubular network organization | IMP | biological_process |
| GO:0072372 | Primary cilium | IDA | cellular_component |
| GO:0072659 | Protein localization to plasma membrane | ISS | biological_process |
| GO:0097051 | Establishment of protein localization to endoplasmic reticulum membrane | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4083158315 | 0.6681643061 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2685758029 |
| GSE13712_SHEAR | Down | -0.0097419828 |
| GSE13712_STATIC | Up | 0.0832124348 |
| GSE19018 | Up | 0.2195856447 |
| GSE19899_A1 | Down | -0.0688067794 |
| GSE19899_A2 | Up | 0.1161506198 |
| PubMed_21979375_A1 | Up | 0.0603933391 |
| PubMed_21979375_A2 | Down | -0.0365781783 |
| GSE35957 | Up | 0.1205487071 |
| GSE36640 | Up | 0.1226344948 |
| GSE54402 | Up | 0.1004255566 |
| GSE9593 | Up | 0.6725344606 |
| GSE43922 | Down | -0.0135747356 |
| GSE24585 | Down | -0.3327409473 |
| GSE37065 | Up | 0.1192433313 |
| GSE28863_A1 | Down | -0.0691899246 |
| GSE28863_A2 | Up | 0.3365986921 |
| GSE28863_A3 | Down | -0.2206724961 |
| GSE28863_A4 | Down | -0.3418429334 |
| GSE48662 | Down | -0.2235569548 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019696 | qRT-PCR;Microarray | Functional MTI (Weak) | 20584986 |
| hsa-miR-148a-3p | MIMAT0000243 | MIRT025986 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037193 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051750 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052065 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
