HCSGD entry for ALDH1L1
1. General information
| Official gene symbol | ALDH1L1 |
|---|---|
| Entrez ID | 10840 |
| Gene full name | aldehyde dehydrogenase 1 family, member L1 |
| Other gene symbols | 10-FTHFDH 10-fTHF FDH FTHFD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | TAS | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0006730 | One-carbon metabolic process | IEA | biological_process |
| GO:0008168 | Methyltransferase activity | IEA | molecular_function |
| GO:0009058 | Biosynthetic process | IEA | biological_process |
| GO:0009258 | 10-formyltetrahydrofolate catabolic process | IEA | biological_process |
| GO:0016155 | Formyltetrahydrofolate dehydrogenase activity | IEA | molecular_function |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0016620 | Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | IEA | molecular_function |
| GO:0016742 | Hydroxymethyl-, formyl- and related transferase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4882398541 | 0.7848798678 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0410679418 |
| GSE13712_SHEAR | Up | 0.0955713944 |
| GSE13712_STATIC | Down | -0.1336681264 |
| GSE19018 | Up | 0.1956521310 |
| GSE19899_A1 | Up | 0.1374608567 |
| GSE19899_A2 | Up | 0.0100010292 |
| PubMed_21979375_A1 | Down | -0.0000792995 |
| PubMed_21979375_A2 | Up | 0.1019016377 |
| GSE35957 | Up | 0.1983953972 |
| GSE36640 | Up | 0.0571927691 |
| GSE54402 | Up | 0.0059306090 |
| GSE9593 | Down | -0.2346433922 |
| GSE43922 | Up | 0.0603346206 |
| GSE24585 | Up | 0.2913819853 |
| GSE37065 | Down | -0.1943244252 |
| GSE28863_A1 | Down | -0.1475683682 |
| GSE28863_A2 | Down | -0.0405496936 |
| GSE28863_A3 | Up | 0.2574562044 |
| GSE28863_A4 | Up | 0.0988743682 |
| GSE48662 | Down | -0.0349205666 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Tetrahydrofolic acid | DB00116 | NUTR00056 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
