HCSGD entry for ALDH1L1

1. General information

Official gene symbolALDH1L1
Entrez ID10840
Gene full namealdehyde dehydrogenase 1 family, member L1
Other gene symbols10-FTHFDH 10-fTHF FDH FTHFD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003824Catalytic activityTASmolecular_function
GO:0005739MitochondrionIEAcellular_component
GO:0006730One-carbon metabolic processIEAbiological_process
GO:0008168Methyltransferase activityIEAmolecular_function
GO:0009058Biosynthetic processIEAbiological_process
GO:000925810-formyltetrahydrofolate catabolic processIEAbiological_process
GO:0016155Formyltetrahydrofolate dehydrogenase activityIEAmolecular_function
GO:0016491Oxidoreductase activityIEAmolecular_function
GO:0016620Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptorIEAmolecular_function
GO:0016742Hydroxymethyl-, formyl- and related transferase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.48823985410.78487986780.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0410679418
GSE13712_SHEARUp0.0955713944
GSE13712_STATICDown-0.1336681264
GSE19018Up0.1956521310
GSE19899_A1Up0.1374608567
GSE19899_A2Up0.0100010292
PubMed_21979375_A1Down-0.0000792995
PubMed_21979375_A2Up0.1019016377
GSE35957Up0.1983953972
GSE36640Up0.0571927691
GSE54402Up0.0059306090
GSE9593Down-0.2346433922
GSE43922Up0.0603346206
GSE24585Up0.2913819853
GSE37065Down-0.1943244252
GSE28863_A1Down-0.1475683682
GSE28863_A2Down-0.0405496936
GSE28863_A3Up0.2574562044
GSE28863_A4Up0.0988743682
GSE48662Down-0.0349205666

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Tetrahydrofolic acidDB00116 NUTR00056

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.