HCSGD entry for NOXA1

1. General information

Official gene symbolNOXA1
Entrez ID10811
Gene full nameNADPH oxidase activator 1
Other gene symbolsNY-CO-31 SDCCAG31 p51NOX
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0006801Superoxide metabolic processIMPbiological_process
GO:0010310Regulation of hydrogen peroxide metabolic processIMPbiological_process
GO:0016176Superoxide-generating NADPH oxidase activator activityIDA IMPmolecular_function
GO:0017124SH3 domain bindingIPImolecular_function
GO:0019899Enzyme bindingIPImolecular_function
GO:0043020NADPH oxidase complexIDAcellular_component
GO:0043085Positive regulation of catalytic activityIDA IMPbiological_process
GO:0048365Rac GTPase bindingIPImolecular_function
GO:0050790Regulation of catalytic activityIDA IMPbiological_process
GO:0060263Regulation of respiratory burstIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.50701927740.61886848900.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1194860779
GSE13712_SHEARUp0.2373859079
GSE13712_STATICDown-0.0583927058
GSE19018Down-0.1458648161
GSE19899_A1Down-0.1841460225
GSE19899_A2Up0.0192455456
PubMed_21979375_A1Down-0.2753880136
PubMed_21979375_A2Down-0.4275258101
GSE35957Up0.0888652984
GSE36640Up0.0400698023
GSE54402Up0.0049573790
GSE9593Up0.1798416663
GSE43922Up0.0857414725
GSE24585Up0.1702535638
GSE37065Down-0.0210352400
GSE28863_A1Down-0.0547857981
GSE28863_A2Up0.0296981827
GSE28863_A3Up0.4021234363
GSE28863_A4Up0.1295505775
GSE48662Up0.1608598545

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.