HCSGD entry for NOXA1

1. General information

Official gene symbolNOXA1
Entrez ID10811
Gene full nameNADPH oxidase activator 1
Other gene symbolsNY-CO-31 SDCCAG31 p51NOX
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0006801Superoxide metabolic processIMPbiological_process
GO:0010310Regulation of hydrogen peroxide metabolic processIMPbiological_process
GO:0016176Superoxide-generating NADPH oxidase activator activityIDA IMPmolecular_function
GO:0017124SH3 domain bindingIPImolecular_function
GO:0019899Enzyme bindingIPImolecular_function
GO:0043020NADPH oxidase complexIDAcellular_component
GO:0043085Positive regulation of catalytic activityIDA IMPbiological_process
GO:0048365Rac GTPase bindingIPImolecular_function
GO:0050790Regulation of catalytic activityIDA IMPbiological_process
GO:0060263Regulation of respiratory burstIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.50701927740.61886848900.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1194860779
GSE13712_SHEARUp0.2373859079
GSE13712_STATICDown-0.0583927058
GSE19018Down-0.1458648161
GSE19899_A1Down-0.1841460225
GSE19899_A2Up0.0192455456
PubMed_21979375_A1Down-0.2753880136
PubMed_21979375_A2Down-0.4275258101
GSE35957Up0.0888652984
GSE36640Up0.0400698023
GSE54402Up0.0049573790
GSE9593Up0.1798416663
GSE43922Up0.0857414725
GSE24585Up0.1702535638
GSE37065Down-0.0210352400
GSE28863_A1Down-0.0547857981
GSE28863_A2Up0.0296981827
GSE28863_A3Up0.4021234363
GSE28863_A4Up0.1295505775
GSE48662Up0.1608598545

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.