HCSGD entry for FARS2
1. General information
| Official gene symbol | FARS2 |
|---|---|
| Entrez ID | 10667 |
| Gene full name | phenylalanyl-tRNA synthetase 2, mitochondrial |
| Other gene symbols | COXPD14 FARS1 HSPC320 PheRS dJ520B18.2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000049 | TRNA binding | IDA IEA | molecular_function |
| GO:0000287 | Magnesium ion binding | IEA | molecular_function |
| GO:0004812 | Aminoacyl-tRNA ligase activity | IEA | molecular_function |
| GO:0004826 | Phenylalanine-tRNA ligase activity | IDA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006418 | TRNA aminoacylation for protein translation | TAS | biological_process |
| GO:0006432 | Phenylalanyl-tRNA aminoacylation | IDA | biological_process |
| GO:0008033 | TRNA processing | IDA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0043039 | TRNA aminoacylation | IEA | biological_process |
Entries Per Page
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8616648646 | 0.5087162532 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0973486001 |
| GSE13712_SHEAR | Down | -0.0481973479 |
| GSE13712_STATIC | Up | 0.0783695365 |
| GSE19018 | Down | -0.1725254278 |
| GSE19899_A1 | Up | 0.0287364091 |
| GSE19899_A2 | Up | 0.1842660168 |
| PubMed_21979375_A1 | Down | -0.3240202902 |
| PubMed_21979375_A2 | Down | -0.0840933144 |
| GSE35957 | Down | -0.2519092682 |
| GSE36640 | Down | -0.2593671351 |
| GSE54402 | Up | 0.0193723687 |
| GSE9593 | Down | -0.1037900969 |
| GSE43922 | Down | -0.0041566132 |
| GSE24585 | Up | 0.1511137641 |
| GSE37065 | Up | 0.1904066145 |
| GSE28863_A1 | Up | 0.0189925000 |
| GSE28863_A2 | Down | -0.0251654519 |
| GSE28863_A3 | Down | -0.1306338704 |
| GSE28863_A4 | Down | -0.0556460000 |
| GSE48662 | Down | -0.0667630549 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Phenylalanine | DB00120 | NUTR00044 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
