HCSGD entry for FARS2


1. General information

Official gene symbolFARS2
Entrez ID10667
Gene full namephenylalanyl-tRNA synthetase 2, mitochondrial
Other gene symbolsCOXPD14 FARS1 HSPC320 PheRS dJ520B18.2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000049TRNA bindingIDA IEAmolecular_function
GO:0000287Magnesium ion bindingIEAmolecular_function
GO:0004812Aminoacyl-tRNA ligase activityIEAmolecular_function
GO:0004826Phenylalanine-tRNA ligase activityIDAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0005759Mitochondrial matrixTAScellular_component
GO:0006418TRNA aminoacylation for protein translationTASbiological_process
GO:0006432Phenylalanyl-tRNA aminoacylationIDAbiological_process
GO:0008033TRNA processingIDAbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0043039TRNA aminoacylationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.86166486460.50871625320.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0973486001
GSE13712_SHEARDown-0.0481973479
GSE13712_STATICUp0.0783695365
GSE19018Down-0.1725254278
GSE19899_A1Up0.0287364091
GSE19899_A2Up0.1842660168
PubMed_21979375_A1Down-0.3240202902
PubMed_21979375_A2Down-0.0840933144
GSE35957Down-0.2519092682
GSE36640Down-0.2593671351
GSE54402Up0.0193723687
GSE9593Down-0.1037900969
GSE43922Down-0.0041566132
GSE24585Up0.1511137641
GSE37065Up0.1904066145
GSE28863_A1Up0.0189925000
GSE28863_A2Down-0.0251654519
GSE28863_A3Down-0.1306338704
GSE28863_A4Down-0.0556460000
GSE48662Down-0.0667630549

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-PhenylalanineDB00120 NUTR00044

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.