HCSGD entry for GLRX3


1. General information

Official gene symbolGLRX3
Entrez ID10539
Gene full nameglutaredoxin 3
Other gene symbolsGLRX4 GRX3 GRX4 PICOT TXNL2 TXNL3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002026Regulation of the force of heart contractionISSbiological_process
GO:0005080Protein kinase C bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005938Cell cortexIEAcellular_component
GO:0009055Electron carrier activityIEAmolecular_function
GO:0010614Negative regulation of cardiac muscle hypertrophyISSbiological_process
GO:0015035Protein disulfide oxidoreductase activityIEAmolecular_function
GO:0030018Z discIEAcellular_component
GO:0045454Cell redox homeostasisIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0051536Iron-sulfur cluster bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09654475130.78485534740.64910222221.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3332419127
GSE13712_SHEARUp0.0724941587
GSE13712_STATICUp0.1671506535
GSE19018Down-0.2063227893
GSE19899_A1Up0.3941134436
GSE19899_A2Up0.4237137240
PubMed_21979375_A1Up0.3925447922
PubMed_21979375_A2Up0.2626432978
GSE35957Down-0.2459744613
GSE36640Down-0.0479600805
GSE54402Up0.5231114952
GSE9593Up0.0805984066
GSE43922Up0.5244402811
GSE24585Down-0.5025725009
GSE37065Down-0.0798523160
GSE28863_A1Up0.1974237991
GSE28863_A2Up0.1697240941
GSE28863_A3Down-0.1812453576
GSE28863_A4Up0.0090975789
GSE48662Down-0.5384823333

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-30a-5pMIMAT0000087MIRT028654ProteomicsFunctional MTI (Weak)18668040
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.